DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Naa80 and Naa80

DIOPT Version :9

Sequence 1:	NP_001014612.1	Gene:	Naa80 / 41195	FlyBaseID:	FBgn0037747	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_062724.1	Gene:	Naa80 / 56441	MGIID:	1888902	Length:	314	Species:	Mus musculus

Alignment Length:	132	Identity:	49/132 - (37%)
Similarity:	74/132 - (56%)	Gaps:	6/132 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 PIHNYPELMKDTCALINAEWPRSETARMRSLEASCDSLPCSLVL----TTEGMCR-VIAHLKLSP 86
            |:|..||||.....|||.:||||..:|:.||..|.|:.|..|:|    .|.|... |:.|.:||.
Mouse    92 PVHCRPELMSACADLINDQWPRSRASRLHSLGQSSDAFPLCLMLLSPQPTPGAAPVVVGHARLSR 156

  Fly    87 INSKKKACFVESVVVDKRHRGQGFGKLIMKFAEDYCRVVLDLKTIYLSTIDQDGFYERIGYEYCA 151
            :..:..:..||:|||.:..||:|||:.:|:..|.:.| ....:.::|:|.||..||..:||:...
Mouse   157 VLDQPHSLLVETVVVARPLRGRGFGRRLMEGLEAFAR-ARGFRRLHLTTHDQLYFYAHLGYQLGE 220

  Fly   152 PI 153
            |:
Mouse   221 PV 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Naa80	NP_001014612.1	Acetyltransf_1	35..147	CDD:395465	41/116 (35%)
Naa80	NP_062724.1	Substrate binding. /evidence=ECO:0000250\|UniProtKB:Q59DX8	118..121		1/2 (50%)
		NAT_SF	148..203	CDD:173926	17/54 (31%)
		Acetyl-CoA binding. /evidence=ECO:0000250\|UniProtKB:Q59DX8	169..171		0/1 (0%)
		Acetyl-CoA binding. /evidence=ECO:0000250\|UniProtKB:Q59DX8	177..182		1/4 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	260..295
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846148
Domainoid	1	1.000	47	1.000	Domainoid score	I11999
eggNOG	1	0.900	-	-		E1_KOG3397
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008051
OrthoInspector	1	1.000	-	-		oto92371
orthoMCL	1	0.900	-	-		OOG6_107957
Panther	1	1.100	-	-	LDO	PTHR13538
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6965
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.700