DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8478 and CG1024

DIOPT Version :9

Sequence 1:	NP_001163576.1	Gene:	CG8478 / 41194	FlyBaseID:	FBgn0037746	Length:	576	Species:	Drosophila melanogaster
Sequence 2:	NP_001138014.2	Gene:	CG1024 / 40789	FlyBaseID:	FBgn0027514	Length:	543	Species:	Drosophila melanogaster

Alignment Length:	399	Identity:	73/399 - (18%)
Similarity:	130/399 - (32%)	Gaps:	101/399 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   210 TEVSNEGVSMLVSPAGAEKEVAHVNEV-----VNEVSELIAKALK------------ISADSVKP 257
            ||:....|:.|.:|....|.:::|:|:     :|...:::.|..|            :..:....
  Fly   193 TEMEKSPVTALAAPVNEPKPISNVSELNLDRCLNAYEDIVRKEEKEVVPKYDDELDALCKEFFDD 257

  Fly   258 ATSKLKVEAGKKRQSMSSTYSGAALPRPRRSYLPTTTAETRTYSFKQRMSVVVKTTLNSPARKRS 322
            ..|..|.||.:::|...:                         ..:|....||...:::..::.
  Fly   258 GPSAGKGEANEEQQQDDA-------------------------HLQQGNQEVVIIEIDALGKEE- 296

  Fly   323 VGGGVSLSRRSCL--PVSKLTKSSIRKSLAVTSVRSPEKIASKPAKTSTKSIPEKV-FSCKNCST 384
                |:..::...  |:|:.||   |:.::.|..|..:      .:.||..:.:.: :.|..|..
  Fly   297 ----VAQLKKEMKSDPISQPTK---RRRISTTPSRDSD------TEMSTNGLTKLISYLCPKCGK 348

  Fly   385 TFRVKSLLDVHM-RMHDPVDNGANTLKRLNSNPVA----------AGVSKNRCKFCDKNFALERA 438
            ..........|: :.||......|:.|.|.|...|          ..|.....|.|.|:......
  Fly   349 EIASMDGWRAHVFKKHDFEHIIENSFKILESGRKAMCLQCREVQPTTVRSQLQKHCFKHLPYRSY 413

  Fly   439 LHIHLMQNCDKIPPSEKRKLEFTELNHEKKAQLPKIGGTSGINHPMTMPQKPQQRISTIPKLA-P 502
            |...|   ||:...|..:.|.....||:::.|               ...|.|..|...|..| |
  Fly   414 LKCTL---CDRTKTSTSKILNHIRYNHQEELQ---------------RKNKTQLLIKPEPMWASP 460

  Fly   503 SQ-GTQSMAPPSVKKIPKNVAHAGVYRTPTKTVPCHICKQSFRSILEFTNHSLTVHGNNQLKKMT 566
            :: |..:||.           .||......:...|..|.:.|||...:..|..:...:...|.:.
  Fly   461 NKSGQAAMAD-----------DAGSEDDQGEQAVCEHCDRVFRSKWRYERHIASCRRSGAGKSVE 514

  Fly   567 GREDAQSAH 575
            |..:|...|
  Fly   515 GTVEALLNH 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8478	NP_001163576.1	zf-C2H2	377..399	CDD:278523	3/22 (14%)
		C2H2 Zn finger	379..399	CDD:275368	3/20 (15%)
		C2H2 Zn finger	426..444	CDD:275368	4/17 (24%)
CG1024	NP_001138014.2	C2H2 Zn finger	30..51	CDD:275368
		C2H2 Zn finger	73..100	CDD:275368
		C2H2 Zn finger	106..123	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100