DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8478 and Zbtb17

DIOPT Version :9

Sequence 1:	NP_001163576.1	Gene:	CG8478 / 41194	FlyBaseID:	FBgn0037746	Length:	576	Species:	Drosophila melanogaster
Sequence 2:	NP_001365755.1	Gene:	Zbtb17 / 22642	MGIID:	107410	Length:	819	Species:	Mus musculus

Alignment Length:	383	Identity:	87/383 - (22%)
Similarity:	135/383 - (35%)	Gaps:	116/383 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 LTQIDDKENTQPEGCG-------GDNSTLSSSVDVTANTVKANTLKTGD----ATMDNVSLQEAA 189
            |:::|....:...|.|       |..:..:||..|.|  ::.:.|.:|.    |:..:...::..
Mouse   147 LSRLDQARGSSSTGPGRELKEERGGQAESASSGPVPA--MEESPLASGQSPNPASRPSSGAEQTE 209

  Fly   190 KTPAPSQVYPLS---------ANVVLENITEVSNEGVSMLVSPA-----GAEKEVAHVNEVVNEV 240
            |..||.:..|:.         |....|.::|.|.:  .|.|.||     |.|:|.|....|..|.
Mouse   210 KADAPREPPPVELKPDPTSSMAAAEAEALSESSEQ--EMEVEPASKGEDGQEEEGAGPATVKEEG 272

  Fly   241 SELIAKALKISADSVKPATSKLKVEAGKKRQSMSSTYSGAALPRPRRSYLPTTTAETRTYSFKQR 305
            ..|         |:.:|.         ::.:..:.|.||..|....:: |.:.|...||.| |..
Mouse   273 MHL---------DNGEPP---------EENEESAGTDSGQELGMEGQN-LRSGTYGDRTES-KAY 317

  Fly   306 MSVVVKT---------TLNSPARKRSVGGGVSLSRRSCLPVSKLTKSSIRKSLAVTSVRSPEKIA 361
            .|::.|.         |.|.....|...|....|.|.|                       .|..
Mouse   318 GSIIHKCEDCGKEFTHTGNFKRHIRIHTGEKPFSCREC-----------------------SKAF 359

  Fly   362 SKPA--KTSTKS-IPEKVFSCKNCSTTFRVKSLLDVHMRMHDPVDNGANTLKRLNSNPVAAGVSK 423
            |.||  |...|: .|.|.:.|:.|..::|:.|||::|.:.|                   :|.::
Mouse   360 SDPAACKAHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRH-------------------SGEAR 405

  Fly   424 NRCKFCDKNFA----LERALHIHLMQ---NCD------KIPPSEKRKLEFTELNHEKK 468
            .||..|.|.|.    |:|...:|..|   .||      ..|.|:.|.||..:.:.|.|
Mouse   406 YRCGDCGKLFTTSGNLKRHQLVHSGQKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHK 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8478	NP_001163576.1	zf-C2H2	377..399	CDD:278523	7/21 (33%)
		C2H2 Zn finger	379..399	CDD:275368	7/19 (37%)
		C2H2 Zn finger	426..444	CDD:275368	7/21 (33%)
Zbtb17	NP_001365755.1	BTB_POZ_ZBTB17_MIZ1	2..113	CDD:349515
		PRK07003	<115..>266	CDD:235906	28/122 (23%)
		COG5048	322..653	CDD:227381	43/184 (23%)
		C2H2 Zn finger	324..344	CDD:275368	3/19 (16%)
		C2H2 Zn finger	352..372	CDD:275368	8/42 (19%)
		C2H2 Zn finger	380..400	CDD:275368	7/19 (37%)
		C2H2 Zn finger	408..428	CDD:275368	6/19 (32%)
		C2H2 Zn finger	436..456	CDD:275368	7/19 (37%)
		C2H2 Zn finger	464..484	CDD:275368	87/383 (23%)
		C2H2 Zn finger	492..512	CDD:275368
		C2H2 Zn finger	520..540	CDD:275368
		C2H2 Zn finger	548..568	CDD:275368
		C2H2 Zn finger	576..596	CDD:275368
		C2H2 Zn finger	604..624	CDD:275368
		C2H2 Zn finger	632..651	CDD:275370
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100