DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Snap24 and SNAP29

DIOPT Version :9

Sequence 1:NP_524298.1 Gene:Snap24 / 41193 FlyBaseID:FBgn0266720 Length:212 Species:Drosophila melanogaster
Sequence 2:NP_004773.1 Gene:SNAP29 / 9342 HGNCID:11133 Length:258 Species:Homo sapiens


Alignment Length:221 Identity:54/221 - (24%)
Similarity:104/221 - (47%) Gaps:20/221 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 PRTELQELQFKSGQVADESLESTRRMLALMDESKEAGIRTLVALDDQGEQLDRIEEGMDRINADM 73
            |....|.|:.:..:.|:.:..||.|.||||.||::.|:.:...|..|...|:|.|:.:|:::.|:
Human    38 PADRQQYLRQEVLRRAEATAASTSRSLALMYESEKVGVASSEELARQRGVLERTEKMVDKMDQDL 102

  Fly    74 REAEKNLSGMEKCCGICVLPWKKVNIKDDGES----------------AWKANDDGKIVASQPQ- 121
            :.::|:::.::...|..|..:|...::...|.                :.....:.|..||.|. 
Human   103 KISQKHINSIKSVFGGLVNYFKSKPVETPPEQNGTLTSQPNNRLKEAISTSKEQEAKYQASHPNL 167

  Fly   122 RVIDERE---RGGMGAPPQSGYVARITNDAREDEMDENLGQVNSMLGNLRNMALDMGSELENQNK 183
            |.:|:.:   ||...|.....|.......|...::|.||.:::..||.|:::||.|.:|:|.|:.
Human   168 RKLDDTDPVPRGAGSAMSTDAYPKNPHLRAYHQKIDSNLDELSMGLGRLKDIALGMQTEIEEQDD 232

  Fly   184 QVDRINAKGDANNIRMDGVNKRANNL 209
            .:||:..|.|..::.:....::...|
Human   233 ILDRLTTKVDKLDVNIKSTERKVRQL 258

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Snap24NP_524298.1 SNARE_SNAP25N_23N 18..82 CDD:277242 19/63 (30%)
SNAP-25 93..148 CDD:395673 12/74 (16%)
SNARE_SNAP25C 150..208 CDD:277238 16/57 (28%)
SNAP29NP_004773.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..41 1/2 (50%)
SNARE_SNAP29N 47..111 CDD:277240 19/63 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 150..191 10/40 (25%)
SNARE_SNAP29C 199..257 CDD:277209 16/57 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3065
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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