DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snap24 and Snap23

DIOPT Version :9

Sequence 1:	NP_524298.1	Gene:	Snap24 / 41193	FlyBaseID:	FBgn0266720	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	XP_038961739.1	Gene:	Snap23 / 64630	RGDID:	620221	Length:	221	Species:	Rattus norvegicus

Alignment Length:	216	Identity:	106/216 - (49%)
Similarity:	145/216 - (67%)	Gaps:	18/216 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 QELQFKSGQVADESLESTRRMLALMDESKEAGIRTLVALDDQGEQLDRIEEGMDRINADMREAEK 78
            :|:|.::.||.|||||||||:|.|..||::|||:|:..||:|||||:|||||||:||.|||||||
  Rat     7 EEIQLRAHQVTDESLESTRRILGLAIESQDAGIKTITMLDEQGEQLNRIEEGMDQINKDMREAEK 71

  Fly    79 NLSGMEKCCGICVLPWKKVNIK-----------DDG---ESAWKANDD---GKIVASQPQRVIDE 126
            .|:.:.||||:||.|..:.::.           :.|   ::.|....|   ..:|:.||.|:.:.
  Rat    72 TLTELNKCCGLCVCPCNRFSVGGCFFETRTKNFESGKNYKATWGDGGDSSPSNVVSKQPSRITNG 136

  Fly   127 RERGGMGAPPQSGYVARITNDAREDEMDENLGQVNSMLGNLRNMALDMGSELENQNKQVDRINAK 191
            :.:...|| ...||:.|||||||||||:|||.||.|:||||:|||||||:|::.||:|:.:|..|
  Rat   137 QPQQTTGA-ASGGYIKRITNDAREDEMEENLTQVGSILGNLKNMALDMGNEIDAQNQQIQKITEK 200

  Fly   192 GDANNIRMDGVNKRANNLLKS 212
            .|.|..|:|..|.||..|:.|
  Rat   201 ADTNKNRIDIANTRAKKLIDS 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snap24	NP_524298.1	SNARE_SNAP25N_23N	18..82	CDD:277242	43/63 (68%)
		SNAP-25	93..148	CDD:395673	16/71 (23%)
		SNARE_SNAP25C	150..208	CDD:277238	34/57 (60%)
Snap23	XP_038961739.1	SNARE_SNAP23N	9..75	CDD:277248	44/65 (68%)
		SNAP-25	100..157	CDD:395673	15/57 (26%)
		SNARE_SNAP23C	159..217	CDD:277237	34/57 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	81	1.000	Domainoid score	I8287
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60093
OrthoDB	1	1.010	-	-		D495812at33208
OrthoFinder	1	1.000	-	-		FOG0000822
OrthoInspector	1	1.000	-	-		mtm9089
orthoMCL	1	0.900	-	-		OOG6_102919
Panther	1	1.100	-	-	O	PTHR19305
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1125
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.930