DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snap24 and zgc:101731

DIOPT Version :9

Sequence 1:	NP_524298.1	Gene:	Snap24 / 41193	FlyBaseID:	FBgn0266720	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_001020729.1	Gene:	zgc:101731 / 447892	ZFINID:	ZDB-GENE-040912-57	Length:	209	Species:	Danio rerio

Alignment Length:	207	Identity:	116/207 - (56%)
Similarity:	151/207 - (72%)	Gaps:	13/207 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 RTELQELQFKSGQVADESLESTRRMLALMDESKEAGIRTLVALDDQGEQLDRIEEGMDRINADMR 74
            |:|::|||.|:.|:.|||||.||.|..|::|||:|||||||.||:|||||||||||:|:||.||:
Zfish     8 RSEVEELQKKANQMTDESLEVTRNMKLLLEESKDAGIRTLVMLDEQGEQLDRIEEGLDQINKDMK 72

  Fly    75 EAEKNLSGMEKCCGICVLPWKKVNIKDDGES-----AWKANDDGKIVASQP-QRVIDERERGGMG 133
            ||||||:.|..|||:|:  |....:||...|     .|..|.|| :|:||| .||:||||:..|
Zfish    73 EAEKNLTDMAMCCGLCI--WPCTKLKDFEASGAYKKVWGNNQDG-VVSSQPSSRVVDEREKMTM- 133

  Fly   134 APPQSGYVARITNDAREDEMDENLGQVNSMLGNLRNMALDMGSELENQNKQVDRINAKGDANNIR 198
               ..||:.|:|||||||||:|||.||.|:|||||:||||||:|::.||.|::||.:|...|..|
Zfish   134 ---SGGYIRRVTNDAREDEMEENLAQVGSILGNLRSMALDMGNEIDTQNVQIERIQSKAVVNESR 195

  Fly   199 MDGVNKRANNLL 210
            ::..|:||..|:
Zfish   196 INEANQRATKLI 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snap24	NP_524298.1	SNARE_SNAP25N_23N	18..82	CDD:277242	45/63 (71%)
		SNAP-25	93..148	CDD:395673	24/60 (40%)
		SNARE_SNAP25C	150..208	CDD:277238	33/57 (58%)
zgc:101731	NP_001020729.1	SNARE_SNAP25N	10..81	CDD:277247	49/70 (70%)
		SNAP-25	91..145	CDD:279208	23/58 (40%)
		SNARE_SNAP23C	147..205	CDD:277237	33/57 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592306
Domainoid	1	1.000	119	1.000	Domainoid score	I5745
eggNOG	1	0.900	-	-		E1_KOG3065
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	231	1.000	Inparanoid score	I3416
OMA	1	1.010	-	-		QHG60093
OrthoDB	1	1.010	-	-		D1197028at2759
OrthoFinder	1	1.000	-	-		FOG0000822
OrthoInspector	1	1.000	-	-		mtm6608
orthoMCL	1	0.900	-	-		OOG6_102919
Panther	1	1.100	-	-	O	PTHR19305
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1125
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.770