DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Snap24 and snap23.1

DIOPT Version :9

Sequence 1:	NP_524298.1	Gene:	Snap24 / 41193	FlyBaseID:	FBgn0266720	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	XP_005158781.1	Gene:	snap23.1 / 393159	ZFINID:	ZDB-GENE-040426-883	Length:	237	Species:	Danio rerio

Alignment Length:	209	Identity:	104/209 - (49%)
Similarity:	147/209 - (70%)	Gaps:	11/209 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LQELQFKSGQVADESLESTRRMLALMDESKEAGIRTLVALDDQGEQLDRIEEGMDRINADMREAE 77
            ::::..::.||.|||||||||||.:.:||:|.|::|:..||:|||||.|:::|||:||.|||:||
Zfish    29 VEDITMRANQVTDESLESTRRMLQMAEESRETGVKTMTMLDEQGEQLRRVDQGMDQINQDMRQAE 93

  Fly    78 KNLSGMEKCCGICVLPWKKV-NIKDDG--ESAWKANDD--------GKIVASQPQRVIDERERGG 131
            |||:.:.||||:||.|.::| :|:.||  :..|....|        |.:|:|||..|.:.:...|
Zfish    94 KNLTDLSKCCGLCVCPCERVTSIEHDGRYKRTWGTGSDNSSTEGKEGGVVSSQPTAVRNGQAVSG 158

  Fly   132 MGAPPQSGYVARITNDAREDEMDENLGQVNSMLGNLRNMALDMGSELENQNKQVDRINAKGDANN 196
            ..:.....|:.|||||||||||:|||.||.|::|||:|:|||||:|::.|||.:|||..|.|.|.
Zfish   159 GSSGASGPYIKRITNDAREDEMEENLDQVGSIIGNLKNLALDMGNEIDKQNKTIDRITDKADMNK 223

  Fly   197 IRMDGVNKRANNLL 210
            .|:|..|:|||.||
Zfish   224 ARIDEANQRANKLL 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snap24	NP_524298.1	SNARE_SNAP25N_23N	18..82	CDD:277242	39/63 (62%)
		SNAP-25	93..148	CDD:395673	19/65 (29%)
		SNARE_SNAP25C	150..208	CDD:277238	34/57 (60%)
snap23.1	XP_005158781.1	SNARE_SNAP25N_23N	34..98	CDD:277242	39/63 (62%)
		SNAP-25	109..175	CDD:279208	19/65 (29%)
		SNARE_SNAP23C	177..235	CDD:277237	34/57 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592302
Domainoid	1	1.000	84	1.000	Domainoid score	I8168
eggNOG	1	0.900	-	-		E1_KOG3065
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60093
OrthoDB	1	1.010	-	-		D495812at33208
OrthoFinder	1	1.000	-	-		FOG0000822
OrthoInspector	1	1.000	-	-		mtm6608
orthoMCL	1	0.900	-	-		OOG6_102919
Panther	1	1.100	-	-	O	PTHR19305
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1125
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.720