DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snap24 and Snap47

DIOPT Version :9

Sequence 1:	NP_524298.1	Gene:	Snap24 / 41193	FlyBaseID:	FBgn0266720	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_955421.1	Gene:	Snap47 / 303183	RGDID:	735194	Length:	419	Species:	Rattus norvegicus

Alignment Length:	317	Identity:	61/317 - (19%)
Similarity:	98/317 - (30%)	Gaps:	131/317 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 GQVADESLESTR--RMLALMDESKEAGIRTLVALDDQGEQLDRIEEGMDRINADMREAEKNLSGM 83
            |..|:.:...||  .::.||..|:.....|...|..||||||.:..|::::.:|:..|::.|:.:
  Rat   107 GTAANPTSPMTRGQELMGLMASSQRRMEDTAKVLHHQGEQLDSVMRGLEKMESDLDVADRLLTEL 171

  Fly    84 EKCC-------------------GICVLPWK--------------------------KVNIKDDG 103
            |...                   .:.|.|.:                          |:.:...|
  Rat   172 ETPSWWPFSAKFWKTPVEAKPRDSVSVAPCEPFGKEGVVIRVPAVVSQRTESHSKPGKLTVLVSG 236

  Fly   104 ESAWKAN------------DD----------------GK-------IVASQPQ------------ 121
            .....::            ||                ||       |.|..|:
  Rat   237 LEIHDSSSLLLHRFEKEDVDDIKVHSPYEVSIRQRFIGKPDVAYRLISAKMPEVIPILEVQFSKK 301

  Fly   122 -------RVIDERER-----GG----------MGAPP--------QSGYVARITND---AREDEM 153
                   .|:..|.|     ||          ||...        |.|..:::..|   ..|.|.
  Rat   302 IELLEDALVLRSRGRASPAEGGCSIRHAASRLMGCTTHQELPTGGQEGQQSQLQKDWPLLSEGEA 366

  Fly   154 DENLGQVNSMLGNLRNMALDMGSELENQNKQVDRINAKGDANNIRMDGVNKRANNLL 210
            .|    :..:|..|:.:|||..:|||.|:..:|.|....|...:.:|..|:|...||
  Rat   367 QE----LTQILSKLKGLALDTEAELERQDAALDGITVAVDRATLTVDKHNRRMRKLL 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snap24	NP_524298.1	SNARE_SNAP25N_23N	18..82	CDD:277242	19/62 (31%)
		SNAP-25	93..148	CDD:395673	20/160 (13%)
		SNARE_SNAP25C	150..208	CDD:277238	18/57 (32%)
Snap47	NP_955421.1	PH-like	12..98	CDD:302622
		SNARE_SNAP47N	106..170	CDD:277241	19/62 (31%)
		SNARE_SNAP47C	359..417	CDD:277207	18/61 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3065
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900