DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Snap24 and sec9

DIOPT Version :9

Sequence 1:	NP_524298.1	Gene:	Snap24 / 41193	FlyBaseID:	FBgn0266720	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_596643.1	Gene:	sec9 / 2540623	PomBaseID:	SPBC26H8.02c	Length:	419	Species:	Schizosaccharomyces pombe

Alignment Length:	223	Identity:	57/223 - (25%)
Similarity:	100/223 - (44%)	Gaps:	35/223 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ENAEPRTELQELQFKSGQVADESLESTRRMLALMDESKEAGIRTLVALDDQGEQLDRIEEGMD-- 67
            |:.|.....|::||    |..:||.|||..|.:...:::.|:.||..|.:|.|::...|:.:|
pombe   191 EDQEVEAIKQKIQF----VKQDSLSSTRNALLMAGNAEQMGLATLANLGEQTEKIATAEKELDIS 251

  Fly    68 RINADMREAE-KNLSGMEKCC-GICV-LPWKKVNIKDDGESAWKANDD--------GKIVASQPQ 121
            :|:|...|.: :.|..:.:.. .|.| .||.|.......|:...|..|        .:..|.:.|
pombe   252 KIHAKRAEEQARELKTLNRSMFAIHVPKPWGKAKRVAAEEARLAAKRDAERQDEMLNRQFAYRSQ 316

  Fly   122 RVIDERERGGMGAPPQSG--------------YVARITNDAREDEMDENLGQVNSMLGNLRNMAL 172
            :.||:..:..|.:..:.|              :.....:||.|.|:|.||.|:.::...|:.:|.
pombe   317 KRIDQAMKDNMKSNKKKGDSKGVSILERSHYQFEPDAEDDAMEKEIDGNLDQIGALATRLKGLAY 381

  Fly   173 DMGSELENQNKQVDRINAKGDANNIRMD 200
            ..|.|:::||.::..|:.|.|    |:|
pombe   382 ATGQEIDSQNARLGSIHDKSD----RLD 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snap24	NP_524298.1	SNARE_SNAP25N_23N	18..82	CDD:277242	20/66 (30%)
		SNAP-25	93..148	CDD:395673	12/76 (16%)
		SNARE_SNAP25C	150..208	CDD:277238	17/51 (33%)
sec9	NP_596643.1	SNARE_SEC9N	200..269	CDD:277239	22/72 (31%)
sec9	NP_596643.1	SNARE_SEC9C	359..417	CDD:277210	17/51 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3065
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	57	1.000	Inparanoid score	I2009
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000822
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19305
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.920