DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mpi and DIN9

DIOPT Version :9

Sequence 1:	NP_649940.1	Gene:	Mpi / 41192	FlyBaseID:	FBgn0286506	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_001319330.1	Gene:	DIN9 / 843027	AraportID:	AT1G67070	Length:	441	Species:	Arabidopsis thaliana

Alignment Length:	421	Identity:	157/421 - (37%)
Similarity:	234/421 - (55%)	Gaps:	55/421 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ELTG---------WVKNYGWGRKGINSAVAQLAMANDPDFRLNEEETYAEMWMGTHVCGVSVVKE 57
            :|||         :||||.||:.|..|.||:|..||... |::.|..|||.|||||..|.|.| |
plant    15 KLTGGEEIQRLRCFVKNYEWGKLGPESLVARLQEANTGQ-RVDSEIPYAEFWMGTHESGPSHV-E 77

  Fly    58 TGE---------------TLD-------RVLKK---DLSYLFKVLSINKALSIQVHPNKCEAERL 97
            .|.               .||       :|:.|   ||.:||||||:.||||||.||||..||:|
plant    78 FGSGHGVSDKCMVTLKSWVLDNPNLLGSKVVDKWGCDLPFLFKVLSVTKALSIQAHPNKALAEKL 142

  Fly    98 HKERPDIYKDPNHKPELAIALTPFLALVGFMSAEDIRDYIDEFQPLSKLIGKEAVDQL---HDST 159
            |:|.|.:|:|.|||||:|:|:|||.||.||::.:::::.|.....:::|:|.:|.||:   |:..
plant   143 HREDPLLYRDNNHKPEIALAVTPFQALCGFVTLKELKEVITNVPEITELVGSKAADQIFNVHEHD 207

  Fly   160 NSESVK----LCYEKLMKTEEPVIAKCISEIAKDYQNELKSNDLLE---VFTKVNKDFPGDVGVL 217
            ..|.:|    |.:.:||........:.:|.:......|.|..:|.|   :..::.|.:.||:||:
plant   208 EDERIKSVVRLIFTQLMSASNNETKQVVSRMKNRLLLETKHRELSEKEKLVLELEKQYTGDIGVI 272

  Fly   218 SLFFLNLIRLQPGQAIYLGANEIHAYLDGDCVECMACSDNVIRAGLTPKYKDVDQLLESVIFESS 282
            |.||.|.::|.||:|:||.|||.|||:.||||||||.||||:|||||||::||..|...:.::..
plant   273 SAFFFNYVKLNPGEALYLDANEPHAYISGDCVECMAASDNVVRAGLTPKHRDVQTLCSMLTYKLG 337

  Fly   283 YKDRKEFIPYRIDDQVQVYIPPVSDFAVINVNIEHSLESYKLEIQAFGSILIVLKGSRILKLKTQ 347
            |.:..:..|  :...|..|:||..:|.|.:.::... :|.........|:.:|::|    |.:.:
plant   338 YPEILKGFP--LTPYVTRYLPPFDEFEVDHCDLPRG-KSTVFPAVPGPSVYLVIEG----KGQLR 395

  Fly   348 QGDKEILVTRGSIVYIPVEAAPEIEFAQSDD 378
            .|..::||.||.::::|.:.  ||......|
plant   396 TGSSKVLVNRGDVLFVPADI--EIHVTGESD 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mpi	NP_649940.1	cupin_like	2..373	CDD:304367	156/414 (38%)
Mpi	NP_649940.1	ManA	3..369	CDD:224399	154/409 (38%)
DIN9	NP_001319330.1	PLN02288	22..419	CDD:215162	153/407 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	242	1.000	Domainoid score	I577
eggNOG	1	0.900	-	-		E1_COG1482
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1825
Inparanoid	1	1.050	254	1.000	Inparanoid score	I1014
OMA	1	1.010	-	-		QHG63421
OrthoDB	1	1.010	-	-		D1043197at2759
OrthoFinder	1	1.000	-	-		FOG0003110
OrthoInspector	1	1.000	-	-		otm3099
orthoMCL	1	0.900	-	-		OOG6_102059
Panther	1	1.100	-	-	LDO	PTHR10309
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2082
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.930