DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mpi and MEE31

DIOPT Version :9

Sequence 1:	NP_649940.1	Gene:	Mpi / 41192	FlyBaseID:	FBgn0286506	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_186906.1	Gene:	MEE31 / 820656	AraportID:	AT3G02570	Length:	432	Species:	Arabidopsis thaliana

Alignment Length:	401	Identity:	140/401 - (34%)
Similarity:	222/401 - (55%)	Gaps:	40/401 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VKNYGWGRKGINSAVAQLAMANDPDFRLNEEETYAEMWMGTHVCGVSVVKE----TGETL----- 62
            ||:|.||:.|.:|.|.::..||. |:.::....|||:|||||..|.|.:::    .|.||
plant    27 VKDYDWGKIGSDSLVYRVYAANS-DYEIDPTRPYAELWMGTHESGPSYLEDADGSNGVTLRSWIT 90

  Fly    63 -------DRVLKK---DLSYLFKVLSINKALSIQVHPNKCEAERLHKERPDIYKDPNHKPELAIA 117
                   :|||:|   ||.:||||||:.:.||||.||:|..|:::||..|::|||.|||||:|:|
plant    91 ENPKSLGNRVLEKWGCDLPFLFKVLSVARPLSIQAHPDKKLAKKMHKAHPNLYKDDNHKPEMALA 155

  Fly   118 LTPFLALVGFMSAEDIRDYIDEFQPLSKLIGKEAVDQL-----HDSTNSES-VKLCYEKLMKTEE 176
            .|.|.||.||:..::::..|.....:.:|:|.|..:|:     ||....:| |:..:..||..:.
plant   156 YTQFEALCGFIPLQELKSVIRAIPEIEELVGSEEANQVFCITEHDEEKVKSVVRTIFTLLMSADA 220

  Fly   177 PVIAKCISEIAKDYQNELKSNDLLE---VFTKVNKDFPGDVGVLSLFFLNLIRLQPGQAIYLGAN 238
            ....|.:|::.:....|.:...|.:   :..|:.|.:|.|:||:|.||.|.::|.||:|:|||||
plant   221 DTTKKIVSKLKRRLHMESQERQLTDKERLVLKLEKQYPNDIGVISAFFFNYVKLNPGEALYLGAN 285

  Fly   239 EIHAYLDGDCVECMACSDNVIRAGLTPKYKDVDQLLESVIFESSYKDRKEFIPYRIDDQVQVYIP 303
            |.||||.|:|:|.||.||||:|||||.|..|:..|...:.::..|.:..:  ..||...:..|:|
plant   286 EPHAYLFGECLEVMATSDNVVRAGLTSKPLDIQTLCSMLSYKLGYPEILK--GTRIRPYITRYLP 348

  Fly   304 PVSDFAVINVNIEHSLESYKLEIQAFGSILIVLKG-SRILKLKTQQGDKEILVTRGSIVYIPVEA 367
            |..:|.|...::.....:....:.. .|:|:||:| .|:....:..|     ::.|.::::|.:.
plant   349 PFEEFEVDLCDLPSGASTVFPSVPG-PSLLLVLQGEGRMSTEASADG-----ISMGDVLFVPADT 407

  Fly   368 APEIEFAQSDD 378
              ||....|.|
plant   408 --EIHLRSSSD 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mpi	NP_649940.1	cupin_like	2..373	CDD:304367	138/394 (35%)
Mpi	NP_649940.1	ManA	3..369	CDD:224399	136/390 (35%)
MEE31	NP_186906.1	PLN02288	25..411	CDD:215162	138/394 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	242	1.000	Domainoid score	I577
eggNOG	1	0.900	-	-		E1_COG1482
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1825
Inparanoid	1	1.050	254	1.000	Inparanoid score	I1014
OMA	1	1.010	-	-		QHG63421
OrthoDB	1	1.010	-	-		D1043197at2759
OrthoFinder	1	1.000	-	-		FOG0003110
OrthoInspector	1	1.000	-	-		otm3099
orthoMCL	1	0.900	-	-		OOG6_102059
Panther	1	1.100	-	-	O	PTHR10309
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2082
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.930