Protein Alignment CG8412 and ALG12

DIOPT Version :9

• Sequence 1: NP_649939.1
• Gene: CG8412 / 41191
• FlyBaseID: FBgn0037743
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_014427.1
• Gene: ALG12 / 855764
• SGDID: S000005313
• Length: 551
• Species: Saccharomyces cerevisiae
• Alignment Length: 477
• Identity: 156/477 - (32%)
• Similarity: 237/477 - (49%)
• Gaps: 55/477 - (11%)

  Fly     1 MDILIFVTAAAHLVYTPFTKVEESFNLQAMHDIL-YLRNNFTQYDHHDYPGVVPRTFIGPLVVSI 64
            :|.::....:.||:..||||||||||:||:|||| |...:.:||||..:||||||||:|.:::::
Yeast     6 LDTVLLTVISFHLIQAPFTKVEESFNIQAIHDILTYSVFDISQYDHLKFPGVVPRTFVGAVIIAM 70

  Fly    65 ISAPFVL---LFETLSINKFWAQYVVRLV--LAGAISVAW--NSLR---QAVTK----------- 108
            :|.|::.   |.:|........|.|||.:  |...:|..:  |.|:   ..:|:
Yeast    71 LSRPYLYLSSLIQTSRPTSIDVQLVVRGIVGLTNGLSFIYLKNCLQDMFDEITEKKKEENEDKDI 135

  Fly   109 -IYGVEVRLWFTAITITQFHFMFYMTRPLPN-IFALPIVLFAIAYWLRDQHKPFIICSGISILVF 171
             ||. ....||....|..||.|||.||.||| :..||:...|:.:.|..::...|..|.:..:||
Yeast   136 YIYD-SAGTWFLLFLIGSFHLMFYSTRTLPNFVMTLPLTNVALGWVLLGRYNAAIFLSALVAIVF 199

  Fly   172 RSEL-ALFLGILLVVSLLRRKVSIDGLLKVALPAGVCILAATVLVDSFFWRRLLWPEGEVLWYNT 235
            |.|: ||..||.| .|::.:|:|:...:|..:.......|.::.|||:||:....||.:...:|.
Yeast   200 RLEVSALSAGIAL-FSVIFKKISLFDAIKFGIFGLGLGSAISITVDSYFWQEWCLPEVDGFLFNV 263

  Fly   236 VLNKSSNWGTSPFLWYF--YSALPRAMGASLVLVPIGVALEP-RIRPLVLSALLFVLLYSILPHK 297
            |...:|.||..|...||  |..:.......|:|...|..|.| :::.:.|::|..:::.|..|||
Yeast   264 VAGYASKWGVEPVTAYFTHYLRMMFMPPTVLLLNYFGYKLAPAKLKIVSLASLFHIIVLSFQPHK 328

  Fly   298 ELRFIIYVFPVLNIAAACACQRIWMNSAKSTWHSFLALA-CGAHLLLNVFITLFLLVISGTNYPG 361
            |.|||||..|.:.:..|.....:|.|.......:.|.|| ....::.:.||::..|.||..||||
Yeast   329 EWRFIIYAVPSIMLLGATGAAHLWENMKVKKITNVLCLAILPLSIMTSFFISMAFLYISRMNYPG 393

  Fly   362 GAALSRLHRL--EAGTSNVSVHISNLAAQSGVSRFMEIN-NEWTYSKDETMNYTQADLVAYTHLL 423
            |.||:..:.:  |...:|.:||||.....:||:.|.|:| ..:..:.|:|.|         |.||
Yeast   394 GEALTSFNDMIVEKNITNATVHISIPPCMTGVTLFGELNYGVYGINYDKTEN---------TTLL 449

  Fly   424 VEAKNKQNTELWASLQNEFDTL 445
                    .|:|.|    ||.|
Yeast   450 --------QEMWPS----FDFL 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8412	NP_649939.1	PMT_2	3..351	CDD:304453	122/376 (32%)
ALG12	NP_014427.1	PMT_2	8..380	CDD:419750	121/373 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345465
Domainoid	1	1.000	173	1.000	Domainoid score	I754
eggNOG	1	0.900	-	-		E1_KOG2516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	208	1.000	Inparanoid score	I824
Isobase	1	0.950	-	0	Normalized mean entropy	S1928
OMA	1	1.010	-	-		QHG55263
OrthoFinder	1	1.000	-	-		FOG0004217
OrthoInspector	1	1.000	-	-		oto99690
orthoMCL	1	0.900	-	-		OOG6_104021
Panther	1	1.100	-	-	LDO	PTHR22760
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2394
SonicParanoid	1	1.000	-	-		X3480
TreeFam	1	0.960	-	-
	15	14.740