Protein Alignment Rpt3R and AFG3

DIOPT Version :10

• Sequence 1: NP_649938.2
• Gene: Rpt3R / 41190
• FlyBaseID: FBgn0037742
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_010933.1
• Gene: AFG3 / 856737
• SGDID: S000000819
• Length: 761
• Species: Saccharomyces cerevisiae
• Alignment Length: 313
• Identity: 111/313 - (35%)
• Similarity: 155/313 - (49%)
• Gaps: 44/313 - (14%)

  Fly   131 PPEAD---------------STISMLSPDEKPDISYSDIGGLDIQKQEIREAVELPLTHAQLYKQ 180
            ||.|:               |...:.:.:....||:.::.|.|..||||.|.|.. |.:...|.:
Yeast   252 PPNANGGGGGGLGGMFNVGKSRAKLFNKETDIKISFKNVAGCDEAKQEIMEFVHF-LKNPGKYTK 315

  Fly   181 IGIDPPRGVLLFGPPGCGKTMLAKAVAHHTTASFIRVVGSEFVQKYLGEGPRMVRDLFRLAKQNS 245
            :|...|||.:|.||||.|||:||||.|......|:.|.|||||:.::|.|...|||||..|:..:
Yeast   316 LGAKIPRGAILSGPPGTGKTLLAKATAGEANVPFLSVSGSEFVEMFVGVGASRVRDLFTQARSMA 380

  Fly   246 PSIIFIDEIDAIATKR--FDAQTGADREVQRILLELLNQMDGFDETTNIKVIMATNRADTLDPAL 308
            ||||||||||||..:|  ..|..||:.|.:..|.:||.:||||..:..:.|:..|||.|.||.||
Yeast   381 PSIIFIDEIDAIGKERGKGGALGGANDEREATLNQLLVEMDGFTTSDQVVVLAGTNRPDVLDNAL 445

  Fly   309 LRPGRLDRKIELPLPDRRQKRLVFTTITSKMNVGEDVDLEDIIARPDKI-------SNADINAIC 366
            :||||.||.|::..||...::.::.....::|: :.:..:|:.....|:       :.|||...|
Yeast   446 MRPGRFDRHIQIDSPDVNGRQQIYLVHLKRLNL-DPLLTDDMNNLSGKLATLTPGFTGADIANAC 509

  Fly   367 QEAGMHAVRENRYVVNAKDFE------------------KGYKTSVRKDEAQH 401
            .||.:.|.|.|...:....||                  |..|.||...||.|
Yeast   510 NEAALIAARHNDPYITIHHFEQAIERVIAGLEKKTRVLSKEEKRSVAYHEAGH 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpt3R	NP_649938.2	PTZ00454	20..405	CDD:240423	111/313 (35%)
AFG3	NP_010933.1	FtsH_ext	124..215	CDD:377663
		FtsH_fam	223..730	CDD:273520	111/313 (35%)