Protein Alignment CG16908 and TTI1

DIOPT Version :9

• Sequence 1: NP_649937.1
• Gene: CG16908 / 41189
• FlyBaseID: FBgn0037741
• Length: 1080
• Species: Drosophila melanogaster
• Sequence 2: NP_001290386.1
• Gene: TTI1 / 9675
• HGNCID: 29029
• Length: 1089
• Species: Homo sapiens
• Alignment Length: 1088
• Identity: 228/1088 - (20%)
• Similarity: 441/1088 - (40%)
• Gaps: 126/1088 - (11%)

  Fly    11 IKPAVEGFIKEPSKDTLSVVERAIEGFNFGEMRIYQVQTVVPLVVKLDELTGENQELRTSLMNCL 75
            ::|......|..:.:.:..::..::..:...::..|...:.||...|.....:.:.|..|::.||
Human    14 LRPVCVQLTKTQTVENVEHLQTRLQAVSDSALQELQQYILFPLRFTLKTPGPKRERLIQSVVECL 78

  Fly    76 SNIVSKTYLADEKGLRSI---LVVVLQQVRDSKTASMRPNLSEEIKLAAVQCIFEALRRSTTDVV 137
            :.::|.|.:.:::.|:.:   |...|......|.|:    :|||:|||.:|.:...:..:..|::
Human    79 TFVLSSTCVKEQELLQELFSELSACLYSPSSQKPAA----VSEELKLAVIQGLSTLMHSAYGDII 139

  Fly   138 ESFYVKETAMVIGQILIMLLEIIEQEKYRKLVQTAIQCLMMVFYVHDESD---QVDVVLRSQVAN 199
            .:||.......:|..:.:||.:.||||.:::...|::||.::....|..|   .:|.:.:.|:.:
Human   140 LTFYEPSILPRLGFAVSLLLGLAEQEKSKQIKIAALKCLQVLLLQCDCQDHPRSLDELEQKQLGD 204

  Fly   200 TIFIFLPKVLIVLFKTSMKDDKVGETIKSMAIQALGRIIC-IMFEETTNEFIKMRYDGDAFRKLF 263
            ....|||.:...|.:....|.|.|.:|...:::...:.:. ||.:|......|::
Human   205 LFASFLPGISTALTRLITGDFKQGHSIVVSSLKIFYKTVSFIMADEQLKRISKVQ---------- 259

  Fly   264 KNNEEAHQCDFTFFASKKATTEQNEERLHQMQTELRSHQWVAATSRHLRPIFAE-MSILRTHSAI 327
                           :|.|.    |.|:.::.. .|...||..|...|..:..: :..:..|...
Human   260 ---------------AKPAV----EHRVAELMV-YREADWVKKTGDKLTILIKKIIECVSVHPHW 304

  Fly   328 RVRESYSDMCCLLLKHCAYNLRGNFLHVLESVLALSEDENEKIAQRCRDTLLLLQQQ------AS 386
            :||....::...||..|:.:|......:|::::.|..||:.:|..:|...|.....|      .:
Human   305 KVRLELVELVEDLLLKCSQSLVECAGPLLKALVGLVNDESPEIQAQCNKVLRHFADQKVVVGNKA 369

  Fly   387 SQDIFDENAEMLLDAHLNKWPRILHRCEDNEQFAELLFFKGFLRNVNTDKLQLLLLVPKNLEMFV 451
            ..||..|:...|    ....||:::..:|..:|:.|....|:|:.:. .|:..:|....:|:...
Human   370 LADILSESLHSL----ATSLPRLMNSQDDQGKFSTLSLLLGYLKLLG-PKINFVLNSVAHLQRLS 429

  Fly   452 TCLLTALDQRPTRDLLNEEYSLRRIREGDSKGLAAELAKLPW-----RQFKYLSSRRTVDILYDI 511
            ..|:..|:.......:.||   ||....|........|..||     |.|::.:..|...:|..:
Human   430 KALIQVLELDVADIKIVEE---RRWNSDDLNASPKTSATQPWNRIQRRYFRFFTDERIFMLLRQV 491

  Fly   512 GALLGTEPTINRLVFDYCQEMIQQRSPSMNECVLLLTLMVT------------------PQEKKA 558
            ..|||....:..|| |:..|:..|......:..::|..:||                  |:|.:.
Human   492 CQLLGYYGNLYLLV-DHFMELYHQSVVYRKQAAMILNELVTGAAGLEVEDLHEKHIKTNPEELRE 555

  Fly   559 RGSRLVLAKLFLDQILRDEHWNLALQPDSAWRLKVNKPTHWFEDRTPGIYSSAIEVRTQDCDSDD 623
                  :....|::....|:|.|..      .|:..:.........||:         |...|.:
Human   556 ------IVTSILEEYTSQENWYLVT------CLETEEMGEELMMEHPGL---------QAITSGE 599

  Fly   624 EQTEVVG------SRVTIADAQFNVLHTCLILDAVGHCARFIGDTFDRHIFLSLHKVLLKVASSN 682
            ...:|..      ...||.....|:...|:.|:.:|..|..:|..|...:..:|:.||.|.....
Human   600 HTCQVTSFLAFSKPSPTICSMNSNIWQICIQLEGIGQFAYALGKDFCLLLMSALYPVLEKAGDQT 664

  Fly   683 TIVHQAASFAFVSMQYALKYAEPSHFIECSTDYITFHLNALLKRSPDSTAAVDILTVVLQYSTRG 747
            .::.|.|:...:.:..|..|....|.|..::||:...::..|:..........:|.|:|:.|...
Human   665 LLISQVATSTMMDVCRACGYDSLQHLINQNSDYLVNGISLNLRHLALHPHTPKVLEVMLRNSDAN 729

  Fly   748 NVPHLDSLFQTIREECSKSHQTTNVHSYLRVFKSFLNHVSDWHDDAAAEVDTELPMQVDEEQNVL 812
            .:|.:..:.|.:.....:.:. ....|::.|..:.:..::.|..| ...:.......:.||.:.|
Human   730 LLPLVADVVQDVLATLDQFYD-KRAASFVSVLHALMAALAQWFPD-TGNLGHLQEQSLGEEGSHL 792

  Fly   813 STWMSVLERPK---------LL-----KDL-NGDTNMGDAEEPAKDEADDADDTEEKP-TKPVLP 861
            :...:.||:..         ||     ||: :|:.:..|.||..:......|:.:.:| .:|.||
Human   793 NQRPAALEKSTTTAEDIEQFLLNYLKEKDVADGNVSDFDNEEEEQSVPPKVDENDTRPDVEPPLP 857

  Fly   862 RHVEMVKDILGQVIKFISTADQGQQIAALECFSSGLPLLADYEDELLPLVHLVWQPLIEKFRQKD 926
            ..:::..|::.:.|..:|..:...::..|:.....:.:|..::::||||.|..|..|:.:..:..
Human   858 LQIQIAMDVMERCIHLLSDKNLQIRLKVLDVLDLCVVVLQSHKNQLLPLAHQAWPSLVHRLTRDA 922

  Fly   927 ALVLNRCFTLLHLLGVHAKDFILKRSLSDVIPQLKQFLKT-ASLHSSTETSQAQTQEYKLQLKLL 990
            .|.:.|.|.:|..||....||:..|...||:|:|...|.| |.:.:......:.|..:||||.:|
Human   923 PLAVLRAFKVLRTLGSKCGDFLRSRFCKDVLPKLAGSLVTQAPISARAGPVYSHTLAFKLQLAVL 987

  Fly   991 KSLADFILGLQIEGRHLHEIMSTVVIYLSQIQPQELQTPARAFFLQLI 1038
            :.|......|.:....|:::....:||||..||.:||..||:.||.|:
Human   988 QGLGPLCERLDLGEGDLNKVADACLIYLSVKQPVKLQEAARSVFLHLM 1035

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16908	NP_649937.1	None
TTI1	NP_001290386.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	826..852		5/25 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144700
Domainoid	1	1.000	189	1.000	Domainoid score	I3286
eggNOG	1	0.900	-	-		E1_KOG4524
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H40969
Inparanoid	1	1.050	190	1.000	Inparanoid score	I3898
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52444
OrthoDB	1	1.010	-	-		D75408at33208
OrthoFinder	1	1.000	-	-		FOG0004672
OrthoInspector	1	1.000	-	-		oto90629
orthoMCL	1	0.900	-	-		OOG6_104423
Panther	1	1.100	-	-	LDO	PTHR18460
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1566
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.800