Protein Alignment Tti1 and TTI1

DIOPT Version :10

• Sequence 1: NP_649937.1
• Gene: Tti1 / 41189
• FlyBaseID: FBgn0037741
• Length: 1080
• Species: Drosophila melanogaster
• Sequence 2: NP_012892.1
• Gene: TTI1 / 853834
• SGDID: S000001516
• Length: 1038
• Species: Saccharomyces cerevisiae
• Alignment Length: 1097
• Identity: 209/1097 - (19%)
• Similarity: 411/1097 - (37%)
• Gaps: 265/1097 - (24%)

  Fly    51 VPLVVKLDE-LTGENQE----------LRTSLMNCLSNIVSKTYLADEKG--LRSILVVVLQQVR 102
            ||:...|.: ..||:|.          |||    |.|   |....:::.|  |..::..::...:
Yeast    65 VPIASLLKQPALGESQTEYVLLIIFHLLRT----CWS---SNGKFSEQLGQQLFPLITFLVSSDK 122

  Fly   103 DSKTASMRPNLSEEIKLAAVQCIFEALRRSTTDVVESFYVKE--------TAMVIGQILIMLLEI 159
            |::....|   |:|.|.|.  |:  .|.:....|....|.||        ....:|..:.:||:|
Yeast   123 DNQKLITR---SDEFKYAG--CL--VLHQFFKSVRSQRYHKEFFSNSKPNLLPALGHSVTILLKI 180

  Fly   160 IEQEKYRKLVQ-TAIQCLMMVFYVHDESDQVDVVLRSQVANTIFIFLPKVLIVLFKTSMKDDK-V 222
            :||......:| .|:..|.::|.        |::...::.:.|   ||..:.|..|...|..: :
Yeast   181 LEQSPQNNELQFKALASLEVLFQ--------DIISDGEMLSFI---LPGNVSVFAKILTKPGRQI 234

  Fly   223 GETIKSMAIQALGRIICIMFEE-----TTNEFIKMRYDGDAFRKLFKNNEEAHQCDFTFFASKKA 282
            ...:....::.|.:::.:::::     ..|:...:|...|...|        |:.:.:|..:...
Yeast   235 HYKVCVRTLEVLAKLLVLVYDDFSLDIKVNKLTDIRELSDTKLK--------HEINQSFMFNGPI 291

  Fly   283 TTEQNEERLHQMQTELRSHQWVAATSRHLR---PIFAEMSILRTHSAIRVRESYSDMCCLLLKHC 344
            ...:.:.:.|      |...|:.|||..:.   ..|....:.|.:.:|  .|:.:....:||..|
Yeast   292 VLLRTDGKTH------RDTSWLTATSGQINIALEAFIPKLLKRNNESI--DEALATFVSILLTRC 348

  Fly   345 AYNLRGNFLHVLESVLALSEDENEKIAQRCRDTLLLLQQQASSQDIFDENAEMLLDAHLNKWPRI 409
            .     |.|:..|.||.              .||:.|::...|:          |.:||.|...:
Yeast   349 E-----NSLNNCEKVLV--------------STLVHLERDPMSK----------LPSHLVKLKEV 384

  Fly   410 LHRCEDNEQFAELLFFKGFLRNVNTDKLQLL----LLVPKNLEM------FVTCLLTALDQ--RP 462
            ::  ||..:.::::.|:      |.|:|..|    .::.||.|.      .|.||..:|::  .|
Yeast   385 VN--EDLHKLSDIIRFE------NADRLSSLSFAITILEKNNERDTMINEVVRCLFESLNESIEP 441

  Fly   463 TRDLLNEEYSLRRIREGDS--------KGLAAELAKLPWRQFKYLSSRRTVDILYDIGALLGTEP 519
            . .|:|.:   .||.|..|        :.|.:..|.:...:.....|.:.....|.:|:||....
Yeast   442 P-SLINHK---ERIIEQSSQLTTTVNFENLESTNALIALPRLSEDMSLKLKKFTYHMGSLLLERH 502

  Fly   520 TINRLVFDYCQEMIQQRSPSMNECVL--LLTLMVTPQEKKARGSRLVLAKLFLDQILRDEHWNLA 582
            .:|.:|.:...|.:.  ||...:.|.  |.|..:...||:.                ::|...|.
Yeast   503 ILNDVVTELISEQVD--SPRTQKIVALWLSTNFIKAMEKQP----------------KEEEVYLQ 549

  Fly   583 LQPDSAWRLKVNKPTHWFEDRTPGIYSSAIE----VRTQDCD--SDDEQTEVVGSRVTIADAQFN 641
            .:.|:.:.                  ||.:|    :..:.|:  |.|...|:.|..:..:| :|.
Yeast   550 FESDANYS------------------SSMVEEVCLIVLEFCNELSQDISMEIEGKGIKKSD-EFA 595

  Fly   642 VLHTCLILDAVGHCARFIGDTFDRHIFLSLHKVLLKVASSNTIVHQAASFAFVSMQYALKYAEP- 705
            |   |.:|.::......:.:.|...:...::.|:..:||.:..:.      :||...||:.|:.
Yeast   596 V---CTVLFSIETICAVMREEFQPELIDYIYTVVDALASPSEAIR------YVSQSCALRIADTL 651

  Fly   706 -----SHFIECSTDYITFHLNALLKRSPDSTAAVDILTVVLQYSTRGNVPHLDSLFQTI------ 759
                 .:.|..:.||:...:::.| .|..:.....||.|:.|.:....:.:...:.:||
Yeast   652 YHGSIPNMILSNVDYLVESISSRL-NSGMTERVSQILMVICQLAGYETIENFKDVIETIFKLLDY 715

  Fly   760 ----REECSKSHQTTNVHSYLRVFKSFLNHVSDWHDDAAAEVDTELPMQVDEE---QNVLSTW-- 815
                .:.|.:..|...: ..|.:.|.::|             |.|:.:::..:   |:..|.|
Yeast   716 YHGYSDLCLQFFQLFKI-IILEMKKKYIN-------------DDEMILKIANQHISQSTFSPWGM 766

  Fly   816 ------MSVLERPKLLKDLNGDTN----MGDAEEPAK---------DEADDADDTEEKP------ 855
                  :::|::...:||...|.|    :.|..||:.         .|.|..||.||:.
Yeast   767 TDFQQVLNILDKETQVKDDITDENDVDFLKDDNEPSNFQEYFDSKLREPDSDDDEEEREEEVEGS 831

  Fly   856 --------TKPVLPRHVEMVKDILGQVIKFISTADQGQQIAALECFSSGLPLLADYEDELLPLVH 912
                    |.|:.....:::..|||...:.::...:..::..|.......|||:...:.|:..|.
Yeast   832 SKEYTDQWTSPIPSDSYKILLQILGYGERLLTHPSKRLRVQILIVMRLIFPLLSTQHNLLIREVA 896

  Fly   913 LVWQPLIEKFRQKDALVLNRCFTLLHLLGVHAKDFILKR--SLSDVIPQ----LKQFLKTASLHS 971
            ..|..:|:.....|..::....:.:..:..::.||:.||  .|...:.|    ||:.....::|:
Yeast   897 STWDSIIQCVLCSDYSIVQPACSCVEQMIKYSGDFVAKRFIELWQKLCQDSFILKELRIDPTVHN 961

  Fly   972 STETSQAQTQEY-KLQLKLLKSLADFIL-GLQIEGRHLHEIMSTVVIYLS-QIQPQE 1025
            ..:.|.::..:: .:....|.|:...:| |::|....:.|.:...:||.. |:.|.|
Yeast   962 HEKKSISKHVKFPPVTENALVSMVHMVLEGVKITEYLISEAVLEQIIYCCIQVVPVE 1018