DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pnn and pnn

DIOPT Version :9

Sequence 1:	NP_001097727.1	Gene:	Pnn / 41185	FlyBaseID:	FBgn0037737	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001005707.1	Gene:	pnn / 448224	XenbaseID:	XB-GENE-6258583	Length:	691	Species:	Xenopus tropicalis

Alignment Length:	313	Identity:	87/313 - (27%)
Similarity:	158/313 - (50%)	Gaps:	29/313 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VDDLEQKLNSAKQSLVILNENIRRIAGRVPKESLQRSEKFKYTQDGKK----------------N 58
            |..|:::|..||:||..::||||::.||.|.|: :.::..:.:..|..                :
Frog     5 VRTLQEQLEKAKESLKNVDENIRKLTGRDPNET-RPAQARRLSLTGPNVVGGRGRGGILLRRGLS 68

  Fly    59 EHNGDRPFPRNATPGGVFK---DKRRMYESKNPISRFPIEENEGRPPRINSRVI--REMPTKKEI 118
            :..|..|..:....|.:.:   ::|:..||:   .....|:.:.:.|.:.|.|:  .:..|::::
Frog    69 DSGGGPPAKQRDFEGALNRLGGERRQRRESR---QESDAEDEDDKKPALQSSVVATSKERTRRDL 130

  Fly   119 VEAQGTDSESRARNRRMFGSLLGTLQKFCQEESRLKSKEDKKAEIDRKVEKQELQERAMLRKQRE 183
            ::.|..|.:.:.||||:||.|:||||||.||.:....::.::.||::|:|.|..:|:..:..:|.
Frog   131 IQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESNVATEQQKRRHEIEQKLEVQAEEEKKQVETERR 195

  Fly   184 TLFLDRKKKQFEIRRLEYKMARMKDFKVWEATMLNAKNNIRTKTKPHLFFRPKVHSPRTEKLLSK 248
            .||.:|:.||.|:|.||.|:......:.|..........||||||||||:.|....|.::||..:
Frog   196 ELFEERRTKQTELRLLEQKVELAHLQEEWNDHNKKIIKYIRTKTKPHLFYIPGRMCPPSQKLFDE 260

  Fly   249 SKSEADVFIEFRREELEVELKNLE----NMNFGKMEDDTAIDESFYEEPDDEE 297
            |:.:.:...|.||.|...:|..:|    ..:....:.:...:|...|..:|:|
Frog   261 SQKKLNAIFESRRLEFAEQLNKMEARPRRQSMKDRDQEKKPEEQNEEHTEDQE 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pnn	NP_001097727.1	Pinin_SDK_memA	126..250	CDD:282541	47/123 (38%)
pnn	NP_001005707.1	Pinin_SDK_N	1..134	CDD:368062	27/132 (20%)
pnn	NP_001005707.1	Pinin_SDK_memA	138..257	CDD:368061	45/118 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	90	1.000	Domainoid score	I7692
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H133908
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005515
OrthoInspector	1	1.000	-	-		oto102524
Panther	1	1.100	-	-	LDO	PTHR12707
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1769
SonicParanoid	1	1.000	-	-		X5120
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.040