DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment side-VII and Cd276

DIOPT Version :9

Sequence 1:	NP_001262432.1	Gene:	side-VII / 41184	FlyBaseID:	FBgn0037736	Length:	939	Species:	Drosophila melanogaster
Sequence 2:	NP_877976.1	Gene:	Cd276 / 315716	RGDID:	727815	Length:	316	Species:	Rattus norvegicus

Alignment Length:	343	Identity:	65/343 - (18%)
Similarity:	126/343 - (36%)	Gaps:	96/343 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 GSKDVPIHQ--IESIVGENIYLPCNVTTYDGD--EPVLVLWYRDDKGTPIYSIDIRAGVSKAPKR 79
            |:.:|.:.:  :.::|..:..|.|:.:...|.  ..:.::|...|....::|  ...|..:....
  Rat    27 GAVEVQVSEDPVVALVDTDATLRCSFSPEPGFSLRQLNLIWQLTDTKQLVHS--FTEGRDQGSAY 89

  Fly    80 WSDDSVFGDRAYFIFDKEPGKLSIQNTQASDSGTYRCRVDFLKAQTINS-RIRLNVISPPKQVII 143
            .:..::|.|    :..:....|.:|..:.:|.|:|.|   |:..|..:| .:.|.|.:|    ..
  Rat    90 ANRTALFPD----LLVQGNASLRLQRVRVTDEGSYTC---FVSIQDFDSAAVSLQVAAP----YS 143

  Fly   144 RDSSNVERSTVVGPYSEGDIVSLKCQVIGGYPTPTISWYRDGIEIPCELSHLAGGKIIECEITLP 208
            :.|..:|.:..:.|   ||:|::.|....|||...:.| :||..:|
  Rat   144 KPSMTLEPNKDLRP---GDMVTITCSSYQGYPEAEVFW-KDGQGLP------------------- 185

  Fly   209 SLGREDLNSRLTCRALSHPRAPI-VEAVVQIDMNFAPLNIRLLGAHQPLSAGRRYDLLCQSA-GS 271
                  |...:|...:::.|... |.:|:::          :|||:...|...|..:|.|.| ||
  Rat   186 ------LTGNVTTSQMANERGLFDVHSVLRV----------VLGANGTYSCLVRNPVLQQDAHGS 234

  Fly   272 ---------RPPAVITWWQNGIRL----------------------EKTTETTSSDGNQTTSTLS 305
                     .||..: |...|:.:                      |:.......||:...|..:
  Rat   235 VTITGQPMTFPPEAL-WVTVGLSVCLVILLVALAFVCWRKIKQSCEEENAGAEDQDGDGEGSKTA 298

  Fly   306 I-----SLSKSDAGKYLS 318
            :     |.:|.|.|:.::
  Rat   299 LRPLKHSENKEDDGQEIA 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
side-VII	NP_001262432.1	IG_like	32..134	CDD:214653	20/104 (19%)
		V-set	32..134	CDD:284989	20/104 (19%)
		IGc2	160..>214	CDD:197706	11/53 (21%)
		Ig	262..328	CDD:299845	17/94 (18%)
		IG_like	264..323	CDD:214653	17/92 (18%)
		IGc2	360..425	CDD:197706
		Ig_3	456..519	CDD:290638
		FN3	538..620	CDD:238020
		FAM176	643..741	CDD:291517
Cd276	NP_877976.1	IG_like	37..138	CDD:214653	20/109 (18%)
		Ig	44..139	CDD:299845	19/103 (18%)
		ig	151..231	CDD:278476	24/118 (20%)
		IG_like	156..238	CDD:214653	27/120 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	281..316		7/34 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000