DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment side-VII and Skint3

DIOPT Version :9

Sequence 1:	NP_001262432.1	Gene:	side-VII / 41184	FlyBaseID:	FBgn0037736	Length:	939	Species:	Drosophila melanogaster
Sequence 2:	NP_001095944.1	Gene:	Skint3 / 195564	MGIID:	3045331	Length:	458	Species:	Mus musculus

Alignment Length:	209	Identity:	44/209 - (21%)
Similarity:	81/209 - (38%)	Gaps:	60/209 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLLLFMLALQLIESSIGSKDVPIHQIESIVGENIYLPCNVTTYDGDEPVLVLWYRDDKGTPIYSI 67
            |.:|.||.|...:.:|...:.|   :.:.:|..:.|.|.::.....:.:.:.|:|:....|:|.
Mouse    15 LCVLQMLVLSSEQFTITGLERP---VLAPLGGILELSCQLSPPQNAQQMEIRWFRNRYTEPVYL- 75

  Fly    68 DIRAG-------VSKAPKRWSDDSVFGDRAYFI-FDKEPGKLSIQ--NTQASDSGTYRC------ 116
             .|.|       :||          :.:|...: .|...||::::  .....|.|:|.|
Mouse    76 -YRNGKDLHGETISK----------YVERTELLKHDIGKGKVTLRVFKVTVDDDGSYHCVFKDGI 129

  Fly   117 ----RVDFLKAQTINSRIRLNVISPPKQVIIRDSSNVERSTVVGPYSEGDIVSLKCQVIGGYPTP 177
                .:..:|....:|.|:: ::.||         |::.            |.|:|...|.:|.|
Mouse   130 FYEEHITEVKVTATSSDIKI-IMHPP---------NIKG------------VMLECHSRGWFPQP 172

  Fly   178 TISWYRD--GIEIP 189
            .:.| ||  |..||
Mouse   173 HMEW-RDSNGQVIP 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
side-VII	NP_001262432.1	IG_like	32..134	CDD:214653	22/121 (18%)
		V-set	32..134	CDD:284989	22/121 (18%)
		IGc2	160..>214	CDD:197706	12/32 (38%)
		Ig	262..328	CDD:299845
		IG_like	264..323	CDD:214653
		IGc2	360..425	CDD:197706
		Ig_3	456..519	CDD:290638
		FN3	538..620	CDD:238020
		FAM176	643..741	CDD:291517
Skint3	NP_001095944.1	IG_like	35..140	CDD:214653	20/119 (17%)
		Ig_MOG_like	42..141	CDD:143190	20/110 (18%)
		Ig	159..221	CDD:299845	12/28 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	44	1.000	Domainoid score	I12214
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000