DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment side-VII and Btnl10

DIOPT Version :9

Sequence 1:	NP_001262432.1	Gene:	side-VII / 41184	FlyBaseID:	FBgn0037736	Length:	939	Species:	Drosophila melanogaster
Sequence 2:	NP_001350343.1	Gene:	Btnl10 / 192194	MGIID:	2182073	Length:	492	Species:	Mus musculus

Alignment Length:	404	Identity:	92/404 - (22%)
Similarity:	157/404 - (38%)	Gaps:	82/404 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LLLFMLALQLIESSIGSKDV----PIHQIESIVGENIYLPCNVTTYDGDEPVLVLWYRDDKGTPI 64
            :|:..:.|||:.|..|..|.    |.|.:.:|||::..|||.::.....|.:.:.||||...:.:
Mouse    14 ILVSFIFLQLLTSGNGKSDFLVLGPPHPLLAIVGQDKELPCKLSLNISAEGMELRWYRDKPSSVV 78

  Fly    65 YSIDIRAGVSKAPKRWSDDSVFGDRAYFIFD-----KEPGKLSIQNTQASDSGTYRCRVDFLKAQ 124
            :       |.|..:...|:.:...:....|:     :....:.|.|....|:|||.|   ..|..
Mouse    79 H-------VYKNGEDVYDEQMVEYKGRTSFNGSHVARGEAAVKIHNVTVFDNGTYHC---VFKEY 133

  Fly   125 TINSRIRLNVISPPKQVIIRDSSNVERSTVVGPYSEGDIVSLKCQVIGGYPTPTISWY-RDGIEI 188
            |.:|:..|.:     :|..|.||  .|..|.....:|  :..:|...|.||.|.:.|. ..|..:
Mouse   134 TSHSQATLWL-----KVAGRGSS--PRIRVTDTQDKG--IRAECTSAGWYPEPKVEWLDLKGQPV 189

  Fly   189 PCELSHL----AGGKIIECEITLPSLGREDLNSRLTCRALSHPRAP--IVEAVVQIDMNFAPLNI 247
            ..| ||.    :.|.:....|..|   ::.....||| ::|:|..|  :.|..:...::..||:
Mouse   190 SAE-SHFSVSASTGLVALLSIVTP---QDTAVGGLTC-SISNPLLPEKVTETYLLASLSRRPLS- 248

  Fly   248 RLLGAHQPLSAGRRYDLLCQSAGSRPPAVITWWQNGIRLE-KTTETTSSDGNQTTSTL---SISL 308
                    ..:|....|:..:.|....|:...:....:.| ||.:.....|.:..:.|   |:||
Mouse   249 --------TESGPALPLILTALGLVSAAIACAFGKCHKEEHKTNQEEEDPGARDEAGLFHVSLSL 305

  Fly   309 SKSDAGKYL--------------------SCKAYNH---AVPSEPLEDG---WKLDIQYVPEAYV 347
            ....|...|                    |.:.:|.   .:..|..|.|   |::::. ...|::
Mouse   306 DPETASPKLMVSEDQKSVKRLLFDQDVFPSSRRFNQDPCILAQERFEAGRHYWEVEVG-DRRAWI 369

  Fly   348 RLGTSLDPSTLREG 361
             ||..|: |.:|||
Mouse   370 -LGVCLE-SLVREG 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
side-VII	NP_001262432.1	IG_like	32..134	CDD:214653	25/106 (24%)
		V-set	32..134	CDD:284989	25/106 (24%)
		IGc2	160..>214	CDD:197706	14/58 (24%)
		Ig	262..328	CDD:299845	15/92 (16%)
		IG_like	264..323	CDD:214653	14/82 (17%)
		IGc2	360..425	CDD:197706	2/2 (100%)
		Ig_3	456..519	CDD:290638
		FN3	538..620	CDD:238020
		FAM176	643..741	CDD:291517
Btnl10	NP_001350343.1	Ig_MOG_like	47..146	CDD:319291	24/113 (21%)
		Ig	151..229	CDD:386229	22/86 (26%)
		SPRY	301..471	CDD:383051	19/84 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	44	1.000	Domainoid score	I12214
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000