Protein Alignment alphaTub85E and TUB4

DIOPT Version :9

• Sequence 1: NP_524297.1
• Gene: alphaTub85E / 41183
• FlyBaseID: FBgn0003886
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_013313.1
• Gene: TUB4 / 850909
• SGDID: S000004202
• Length: 473
• Species: Saccharomyces cerevisiae
• Alignment Length: 481
• Identity: 142/481 - (29%)
• Similarity: 227/481 - (47%)
• Gaps: 57/481 - (11%)

  Fly     3 ECISVHIGQAGVQIGNACWELYCLEHGIQPDG--HMPSDKTVGGGDDSFSTFFSETGAGKHVPRA 65
            |.|::..||.|..:|...|.....||.|..||  .:|...|  ..||....||.|....|..|||
Yeast     4 EIITLQAGQCGNHVGKFLWSQLAKEHAIGTDGLSQLPDSST--ERDDDTKPFFRENSRNKFTPRA 66

  Fly    66 VFVDLEPTVVDEVRTGTYRQLFHPEQLITGKE--DAANNYARGHYTIGKEIVDVVLDRIRKLADQ 128
            :.:|.||:|:.:|. .|:|..|.|.......:  .|.|::|.| |.||....|.:|::|.|..|.
Yeast    67 IMMDSEPSVIADVE-NTFRGFFDPRNTWVASDGASAGNSWANG-YDIGTRNQDDILNKIDKEIDS 129

  Fly   129 CTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHT 193
            ....:||.:.||..||||||..|.|:|.|...|.||....:|::|| :.|..||:.||:||....
Yeast   130 TDNFEGFQLLHSVAGGTGSGLGSNLLEALCDRYPKKILTTYSVFPA-RSSEVVVQSYNTILALRR 193

  Fly   194 TLEHSDCAFMVDNEAIYDICRR-----NLDIERPTYMNLNRLIGQIVSSITASLRFDGALNVDLT 253
            .:|.||...:.||.::.:|..:     |:|::     :.|:||..|:||:|.|:||...:...::
Yeast   194 LIEDSDATVVFDNASLLNISGKVFRNPNIDLQ-----HTNQLISTIISSVTNSIRFPSYMYSSMS 253

  Fly   254 EFQTNLVPYPRIHFPLATYAPVIS---VEKAYHEQLTVAEITNACFEPANQMVKCDPRRGKYMAC 315
            ...:.|:|.|.:||...::.|..|   .:...|:..:..::.....:|:|.:|........|...
Yeast   254 SIYSTLIPSPELHFLSPSFTPFTSDYIHDDIAHKGHSSYDVMLDLLDPSNSLVSTAMNNPTYFNV 318

  Fly   316 CMLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTV--------VPGGDLAKVQ 372
            .....|:|.|:.::.|:.  |.::.|:|..|..:...|.|..:.|.:        |.|
Yeast   319 YNTIIGNVEPRQISRAMT--KLQQRIKFPSWSSSAMHVNIGRRSPYLPLQPNENEVSG------- 374

  Fly   373 RAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWY-VGEGME-----EGEFAEAREDLAALEKD 431
               .||||.:.:...:....:.||.::||.||::.| ||:..:     :.||||:||.:.:|.:|
Yeast   375 ---MMLSNMSTVVNVFENACNTFDKVFAKGAFLNNYNVGDLFQSMQNVQDEFAESREVVQSLMED 436

  Fly   432 Y---------EEVGIDSTTELGEDEE 448
            |         ::|.:|....:||.||
Yeast   437 YVAAEQDSYLDDVLVDDENMVGELEE 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub85E	NP_524297.1	PTZ00335	1..448	CDD:185562	140/479 (29%)
TUB4	NP_013313.1	COG5023	2..456	CDD:227356	138/473 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810