Protein Alignment alphaTub85E and TUBA1C

DIOPT Version :9

• Sequence 1: NP_524297.1
• Gene: alphaTub85E / 41183
• FlyBaseID: FBgn0003886
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_001290043.1
• Gene: TUBA1C / 84790
• HGNCID: 20768
• Length: 519
• Species: Homo sapiens
• Alignment Length: 448
• Identity: 424/448 - (94%)
• Similarity: 436/448 - (97%)
• Gaps: 0/448 - (0%)

  Fly     2 RECISVHIGQAGVQIGNACWELYCLEHGIQPDGHMPSDKTVGGGDDSFSTFFSETGAGKHVPRAV 66
            |||||:|:|||||||||||||||||||||||||.||||||:|||||||:||||||||||||||||
Human    72 RECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAV 136

  Fly    67 FVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDVVLDRIRKLADQCTG 131
            ||||||||:|||||||||||||||||||||||||||||||||||||||:|:||||||||||||||
Human   137 FVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTG 201

  Fly   132 LQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLE 196
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human   202 LQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLE 266

  Fly   197 HSDCAFMVDNEAIYDICRRNLDIERPTYMNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVP 261
            ||||||||||||||||||||||||||||.||||||.|||||||||||||||||||||||||||||
Human   267 HSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVP 331

  Fly   262 YPRIHFPLATYAPVISVEKAYHEQLTVAEITNACFEPANQMVKCDPRRGKYMACCMLYRGDVVPK 326
            ||||||||||||||||.||||||||||||||||||||||||||||||.|||||||:|||||||||
Human   332 YPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPK 396

  Fly   327 DVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARL 391
            |||||||||||||:|||||||||||||||||||||||||||||||||||||||||||:|||||||
Human   397 DVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAVAEAWARL 461

  Fly   392 DHKFDLMYAKRAFVHWYVGEGMEEGEFAEAREDLAALEKDYEEVGIDSTTELGEDEEY 449
            |||||||||||||||||||||||||||:|||||:|||||||||||.||.....|.|||
Human   462 DHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGADSADGEDEGEEY 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub85E	NP_524297.1	PTZ00335	1..448	CDD:185562	421/445 (95%)
TUBA1C	NP_001290043.1	PTZ00335	72..518	CDD:185562	421/445 (95%)
		alpha_tubulin	72..505	CDD:276955	415/432 (96%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165142867
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54134
OrthoDB	1	1.010	-	-		D275336at33208
OrthoFinder	1	1.000	-	-		FOG0000082
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100108
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X95
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.660