DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTub85E and TUA1

DIOPT Version :9

Sequence 1:	NP_524297.1	Gene:	alphaTub85E / 41183	FlyBaseID:	FBgn0003886	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	NP_176654.1	Gene:	TUA1 / 842782	AraportID:	AT1G64740	Length:	450	Species:	Arabidopsis thaliana

Alignment Length:	448	Identity:	351/448 - (78%)
Similarity:	404/448 - (90%)	Gaps:	2/448 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRECISVHIGQAGVQIGNACWELYCLEHGIQPDGHMPSDKTVGGGDDSFSTFFSETGAGKHVPRA 65
            |||.||:||||||:|:||:|||||||||||||||.||||.|||...|:|:||||||.:|:|||||
plant     1 MREIISIHIGQAGIQVGNSCWELYCLEHGIQPDGTMPSDSTVGACHDAFNTFFSETSSGQHVPRA 65

  Fly    66 VFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDVVLDRIRKLADQCT 130
            ||:||||||:||||||||||||||||||:||||||||:||||||:|:||||..|:|:|||||.||
plant    66 VFLDLEPTVIDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTVGREIVDTCLERLRKLADNCT 130

  Fly   131 GLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTL 195
            ||||||||::.|||||||..|||:||||||:||||||.|:|||:|||||||||||||:|:||:.|
plant   131 GLQGFLVFNAVGGGTGSGLGSLLLERLSVDFGKKSKLGFTIYPSPQVSTAVVEPYNSVLSTHSLL 195

  Fly   196 EHSDCAFMVDNEAIYDICRRNLDIERPTYMNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLV 260
            ||:|...::|||||||||||:||||||||.||||||.|.:||:|.|||||||:|||:||||||||
plant   196 EHTDVVVLLDNEAIYDICRRSLDIERPTYSNLNRLISQTISSLTTSLRFDGAINVDITEFQTNLV 260

  Fly   261 PYPRIHFPLATYAPVISVEKAYHEQLTVAEITNACFEPANQMVKCDPRRGKYMACCMLYRGDVVP 325
            |||||||.|::||||||..||||||.:|.|||.:.|||:|.|.|||||.|||||||::|||||||
plant   261 PYPRIHFMLSSYAPVISSAKAYHEQFSVPEITTSVFEPSNMMAKCDPRHGKYMACCLMYRGDVVP 325

  Fly   326 KDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWAR 390
            ||||.|:|.||.||:||||||||||||.|||||||:||||||||||||||||:||.||:||.::|
plant   326 KDVNTAVAAIKAKRTIQFVDWCPTGFKCGINYQPPSVVPGGDLAKVQRAVCMISNNTAVAEVFSR 390

  Fly   391 LDHKFDLMYAKRAFVHWYVGEGMEEGEFAEAREDLAALEKDYEEVGIDSTTELGEDEE 448
            :||||||||:||||||||||||||||||:|||||||||||||||||.:...:  :|||
plant   391 IDHKFDLMYSKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGGEGAED--DDEE 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub85E	NP_524297.1	PTZ00335	1..448	CDD:185562	349/446 (78%)
TUA1	NP_176654.1	PLN00221	1..435	CDD:177802	345/433 (80%)
TUA1	NP_176654.1	alpha_tubulin	2..435	CDD:276955	344/432 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	391	1.000	Domainoid score	I145
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	814	1.000	Inparanoid score	I81
OMA	1	1.010	-	-		QHG54134
OrthoDB	1	1.010	-	-		D514396at2759
OrthoFinder	1	1.000	-	-		FOG0000082
OrthoInspector	1	1.000	-	-		mtm1063
orthoMCL	1	0.900	-	-		OOG6_100108
Panther	1	1.100	-	-	O	PTHR11588
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X95
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.880