Protein Alignment alphaTub85E and TUBA4A

DIOPT Version :10

• Sequence 1: NP_524297.1
• Gene: alphaTub85E / 41183
• FlyBaseID: FBgn0003886
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: XP_047301630.1
• Gene: TUBA4A / 7277
• HGNCID: 12407
• Length: 457
• Species: Homo sapiens
• Alignment Length: 447
• Identity: 419/447 - (93%)
• Similarity: 432/447 - (96%)
• Gaps: 0/447 - (0%)

  Fly     2 RECISVHIGQAGVQIGNACWELYCLEHGIQPDGHMPSDKTVGGGDDSFSTFFSETGAGKHVPRAV 66
            |||||||:||||||:||||||||||||||||||.||||||:|||||||:|||.||||||||||||
Human    11 RECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGKHVPRAV 75

  Fly    67 FVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDVVLDRIRKLADQCTG 131
            ||||||||:||:|.|.||||||||||||||||||||||||||||||||:|.||||||||:|||||
Human    76 FVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLDRIRKLSDQCTG 140

  Fly   132 LQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLE 196
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human   141 LQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLE 205

  Fly   197 HSDCAFMVDNEAIYDICRRNLDIERPTYMNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVP 261
            ||||||||||||||||||||||||||||.||||||.|||||||||||||||||||||||||||||
Human   206 HSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVP 270

  Fly   262 YPRIHFPLATYAPVISVEKAYHEQLTVAEITNACFEPANQMVKCDPRRGKYMACCMLYRGDVVPK 326
            ||||||||||||||||.||||||||:|||||||||||||||||||||.|||||||:|||||||||
Human   271 YPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPK 335

  Fly   327 DVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARL 391
            |||||||.|||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human   336 DVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARL 400

  Fly   392 DHKFDLMYAKRAFVHWYVGEGMEEGEFAEAREDLAALEKDYEEVGIDSTTELGEDEE 448
            |||||||||||||||||||||||||||:|||||:||||||||||||||..:..|.||
Human   401 DHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGIDSYEDEDEGEE 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub85E	NP_524297.1	PTZ00335	1..448	CDD:185562	417/445 (94%)
TUBA4A	XP_047301630.1	PTZ00335	11..457	CDD:185562	417/445 (94%)