Protein Alignment alphaTub85E and Tubb6

DIOPT Version :10

• Sequence 1: NP_524297.1
• Gene: alphaTub85E / 41183
• FlyBaseID: FBgn0003886
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_080749.2
• Gene: Tubb6 / 67951
• MGIID: 1915201
• Length: 447
• Species: Mus musculus
• Alignment Length: 451
• Identity: 183/451 - (40%)
• Similarity: 269/451 - (59%)
• Gaps: 13/451 - (2%)

  Fly     1 MRECISVHIGQAGVQIGNACWELYCLEHGIQPDGHMPSDKTVGGGDDSFSTFFSETGAGKHVPRA 65
            |||.:.:..||.|.|||...||:...||||...|....|..:  ..:..|.:::|:.:.|:||||
Mouse     1 MREIVHIQAGQCGNQIGTKFWEVISDEHGIDQAGGYVGDSAL--QLERISVYYNESSSKKYVPRA 63

  Fly    66 VFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDVVLDRIRKLADQCT 130
            ..|||||..:|.||:|.:.|||.|:..|.|:..|.||:|:||||.|.|:||.|||.:||..:.|.
Mouse    64 ALVDLEPGTMDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAELVDSVLDVVRKECEHCD 128

  Fly   131 GLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTL 195
            .||||.:.||.|||||||..:||:.::..:|..:....||:.|:|:||..||||||:.|:.|..:
Mouse   129 CLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLV 193

  Fly   196 EHSDCAFMVDNEAIYDICRRNLDIERPTYMNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLV 260
            |::|..:.:||||:||||.|.|.:..|||.:||.|:...:|.:|.||||.|.||.||.:...|:|
Mouse   194 ENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMV 258

  Fly   261 PYPRIHFPLATYAPVISVEKAYHEQLTVAEITNACFEPANQMVKCDPRRGKYMACCMLYRGDVVP 325
            |:||:||.:..:||:.:.....:..|||.|:|...|:..|.|..||||.|:|:....::||.:..
Mouse   259 PFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVATVFRGPMSM 323

  Fly   326 KDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWAR 390
            |:|:..:..|:.|.|..||:|.|...||.:...||        ..::.|...:.|:|||.|.:.|
Mouse   324 KEVDEQMLAIQNKNSSYFVEWIPNNVKVAVCDIPP--------RGLKMASTFIGNSTAIQELFKR 380

  Fly   391 LDHKFDLMYAKRAFVHWYVGEGMEEGEFAEAR---EDLAALEKDYEEVGIDSTTELGEDEE 448
            :..:|..|:.::||:||:.||||:|.||.||.   .||.:..:.|::..::...|..|||:
Mouse   381 ISEQFSAMFRRKAFLHWFTGEGMDEMEFTEAESNMNDLVSEYQQYQDATVNDGEEAFEDED 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub85E	NP_524297.1	PTZ00335	1..448	CDD:185562	182/449 (41%)
Tubb6	NP_080749.2	PLN00220	1..431	CDD:215107	179/439 (41%)
		MREI motif. /evidence=ECO:0000250|UniProtKB:P07437	1..4		2/2 (100%)