Protein Alignment alphaTub85E and Tubd1

DIOPT Version :10

• Sequence 1: NP_524297.1
• Gene: alphaTub85E / 41183
• FlyBaseID: FBgn0003886
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_001185974.1
• Gene: Tubd1 / 56427
• MGIID: 1891826
• Length: 486
• Species: Mus musculus
• Alignment Length: 538
• Identity: 112/538 - (20%)
• Similarity: 204/538 - (37%)
• Gaps: 162/538 - (30%)

  Fly     5 ISVHIGQAGVQIGNACWELYCLEHGIQPDGHMPSDKTVGGGDDSFST-----FFSETGAGKHVPR 64
            ::|.:||.|.|||   :|::   ..:..|.|..........::::..     ||.|...|..|.|
Mouse     4 VTVQLGQCGNQIG---FEVF---DALFRDSHCSQGLCSKRDNEAYQASCRERFFREEENGVPVAR 62

  Fly    65 AVFVDLEPTVVDE-----VRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDVVLDRIRK 124
            ||.||:||.|:::     .::|.:....|..  ...|:.:.||:|.|:...|.:..:.:::.|:.
Mouse    63 AVLVDMEPKVINQTLSKAAQSGRWNYGQHTS--FCQKQGSGNNWAYGYSVHGPKHEESIMNLIQT 125

  Fly   125 LADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSIL 189
            ..::|..|.||.:..|..||||||..:.:.::|...|....|:...|:|. .....:|:.|||||
Mouse   126 EVEKCDSLSGFFIIMSMAGGTGSGLGAFVTQKLQDQYSSSLKMNQIIWPY-GTGEVIVQNYNSIL 189

  Fly   190 TTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYMNLNRLIGQIVSSI-------TASLRFD-- 245
            |.......||...:.:|:|::.||.:.::|::.::.:||:::...:.|:       .:|..:.
Mouse   190 TLSHLYRSSDALLIHENDAVHKICAKRMNIKQISFRDLNQVLAHQLGSVFQPTYSEDSSFHYRRN 254

  Fly   246 ----------------------GALNV-------DLTEFQTNLVPYP------------------ 263
                                  .|.|:       ||.|   :|||:|
Mouse   255 PLDSGTVGPQACLMPRIFVWSLSATNLSFYPQTGDLME---HLVPHPEFKMLGVRNIPQMSAASL 316

  Fly   264 ------------------------------RIHFPLATYAPV--ISVEKAYHEQLTVA------- 289
                                          ::..||....|:  .|..|.:|...::|
Mouse   317 AYSAFTWAGLLKHLRQMLISSAKMEEGINWQVRPPLTGLPPIGKASAHKEHHFNTSLANLVVLRG 381

  Fly   290 -EITNACFEPANQMVKCDPRRGKYMACCMLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKV 353
             |:.:|..|...     ||         .||...:.|.|   |.:..||:|:..
Mouse   382 REVHSADVEGFK-----DP---------ALYTSWLEPVD---AFSVWKTQRAFD----------- 418

  Fly   354 GINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEF 418
                            |.:::..::||:..:.:....:..|...|::.:||:|.|...||||.:|
Mouse   419 ----------------KYEKSAALVSNSQLLVKPLDMIVGKAWNMFSSKAFIHQYTKFGMEEEDF 467

  Fly   419 AEAREDLAALEKDYEEVG 436
            .::...|..:...|..:|
Mouse   468 LDSFALLEQVVASYGSLG 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub85E	NP_524297.1	PTZ00335	1..448	CDD:185562	112/538 (21%)
Tubd1	NP_001185974.1	delta_zeta_tubulin-like	2..483	CDD:276958	111/534 (21%)