Protein Alignment alphaTub85E and tubb1

DIOPT Version :10

• Sequence 1: NP_524297.1
• Gene: alphaTub85E / 41183
• FlyBaseID: FBgn0003886
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_001313351.1
• Gene: tubb1 / 558552
• ZFINID: ZDB-GENE-110408-5
• Length: 466
• Species: Danio rerio
• Alignment Length: 448
• Identity: 186/448 - (41%)
• Similarity: 271/448 - (60%)
• Gaps: 11/448 - (2%)

  Fly     1 MRECISVHIGQAGVQIGNACWELYCLEHGIQPDGHMPSDKTVGGGDDSFSTFFSETGAGKHVPRA 65
            |||.:.:.|||.|.|||:..||:...||||...|....|..:  ..:..:.:|:|...||:||||
Zfish     1 MREIVHLQIGQCGNQIGSKFWEVISDEHGINRVGAYEGDMDL--QLERVNVYFNEAHGGKYVPRA 63

  Fly    66 VFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDVVLDRIRKLADQCT 130
            :.|||||..:|.||.....|||.|:..|.|...|.||:|:||||.|.|:|:.|:||:|..|:.|.
Zfish    64 LLVDLEPGTMDSVRGSQIGQLFRPDNFIHGNSGAGNNWAKGHYTEGAELVEQVVDRVRNEAESCD 128

  Fly   131 GLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTL 195
            .:|||...||.|||||||..:|::.::..:|..:....||:.|:|:||..||||||:.|:.|..:
Zfish   129 CMQGFQFVHSLGGGTGSGMGTLIINKIREEYPDRIMNSFSVMPSPKVSDTVVEPYNATLSIHQLI 193

  Fly   196 EHSDCAFMVDNEAIYDICRRNLDIERPTYMNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLV 260
            |::|..:.:||||:||||.|.|.:..|||.:||.|:...:|.:|.||||.|.||.||.:...|:|
Zfish   194 ENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSLTMSGVTTSLRFPGQLNADLRKLAVNMV 258

  Fly   261 PYPRIHFPLATYAPVISVEKAYHEQLTVAEITNACFEPANQMVKCDPRRGKYMACCMLYRGDVVP 325
            |:||:||.:..:||:.:.....:..|||.|:|...|:|.|.|..||||||:|:....::||.:..
Zfish   259 PFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDPRNMMTACDPRRGRYLTVAGIFRGRMST 323

  Fly   326 KDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWAR 390
            |:|:..:..|:.|.|..||||.|...||.:...||        ..::.|...:.|.|||.|.:.|
Zfish   324 KEVDEQMLAIQQKNSNYFVDWIPHNVKVAVCDIPP--------RGLKMASTFIGNNTAIQEVFKR 380

  Fly   391 LDHKFDLMYAKRAFVHWYVGEGMEEGEFAEAREDLAALEKDYEEVGIDSTTELGEDEE 448
            :..:|.||:.::||:|||.||||:|.||:||..:|..|..:|::.. |:|.::..:||
Zfish   381 IGEQFALMFRRKAFLHWYTGEGMDELEFSEAESNLNDLVSEYQQYQ-DATADMDYEEE 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub85E	NP_524297.1	PTZ00335	1..448	CDD:185562	184/446 (41%)
tubb1	NP_001313351.1	PTZ00010	1..433	CDD:240228	184/442 (42%)