Protein Alignment alphaTub85E and tubb2

DIOPT Version :10

• Sequence 1: NP_524297.1
• Gene: alphaTub85E / 41183
• FlyBaseID: FBgn0003886
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_001019593.1
• Gene: tubb2 / 554127
• ZFINID: ZDB-GENE-050522-384
• Length: 449
• Species: Danio rerio
• Alignment Length: 448
• Identity: 179/448 - (39%)
• Similarity: 268/448 - (59%)
• Gaps: 10/448 - (2%)

  Fly     1 MRECISVHIGQAGVQIGNACWELYCLEHGIQPDGHMPSDKTVGGGDDSFSTFFSETGAGKHVPRA 65
            |||.:.:..||.|.|||...||:...||||.|.|....|..:  ..:..:.:::|....|.||||
Zfish     1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYQGDSEL--QLERINVYYNEASGNKFVPRA 63

  Fly    66 VFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDVVLDRIRKLADQCT 130
            :.|||||..:|.||:|.:.|:|.|:..:.|:..|.||:|:||||.|.|:||.|||.:||.::.|.
Zfish    64 ILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESENCD 128

  Fly   131 GLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTL 195
            .||||.:.||.|||||||..:||:.::..:|..:....||:.|:|:||..||||||:.|:.|..:
Zfish   129 CLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLV 193

  Fly   196 EHSDCAFMVDNEAIYDICRRNLDIERPTYMNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLV 260
            |::|..|.:||||:||||.|.|.:..|||.:||.|:...:|.:|..|||.|.||.||.:...|:|
Zfish   194 ENTDETFSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMV 258

  Fly   261 PYPRIHFPLATYAPVISVEKAYHEQLTVAEITNACFEPANQMVKCDPRRGKYMACCMLYRGDVVP 325
            |:||:||.:..:||:.|.....:..|:|.|:|...|:..|.|..||||.|:|:....::||.:..
Zfish   259 PFPRLHFFMPGFAPLTSRGSQQYRALSVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSM 323

  Fly   326 KDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWAR 390
            |:|:..:.:::.|.|..||:|.|...|..:...||        ..::.:...:.|:|||.|.:.|
Zfish   324 KEVDEQMLSVQNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMSATFIGNSTAIQELFRR 380

  Fly   391 LDHKFDLMYAKRAFVHWYVGEGMEEGEFAEAREDLAALEKDYEEVGIDSTTELGEDEE 448
            :..:|..|:.::||:|||.||||:|.||.||..::..|..:|::....:..|:||.||
Zfish   381 ISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVFEYQQYQDATADEMGEYEE 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub85E	NP_524297.1	PTZ00335	1..448	CDD:185562	177/446 (40%)
tubb2	NP_001019593.1	PLN00220	1..434	CDD:215107	175/442 (40%)