DRSC/TRiP Functional Genomics Resources

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Protein Alignment alphaTub85E and tubb2b

DIOPT Version :10

Sequence 1:NP_524297.1 Gene:alphaTub85E / 41183 FlyBaseID:FBgn0003886 Length:449 Species:Drosophila melanogaster
Sequence 2:NP_989275.1 Gene:tubb2b / 394889 XenbaseID:XB-GENE-491121 Length:445 Species:Xenopus tropicalis


Alignment Length:450 Identity:182/450 - (40%)
Similarity:268/450 - (59%) Gaps:14/450 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MRECISVHIGQAGVQIGNACWELYCLEHGIQPDG--HMPSDKTVGGGDDSFSTFFSETGAGKHVP 63
            |||.:.:..||.|.|||...||:...||||.|.|  |..||..:    :..:.:::|....|.||
 Frog     1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQL----ERINVYYNEATGNKFVP 61

  Fly    64 RAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDVVLDRIRKLADQ 128
            ||:.|||||..:|.||:|.:.|:|.|:..:.|:..|.||:|:||||.|.|:||.|||.:||.|:.
 Frog    62 RAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAES 126

  Fly   129 CTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHT 193
            |..||||.:.||.|||||||..:||:.::..:|..:....||:.|:|:||..||||||:.|:.|.
 Frog   127 CDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQ 191

  Fly   194 TLEHSDCAFMVDNEAIYDICRRNLDIERPTYMNLNRLIGQIVSSITASLRFDGALNVDLTEFQTN 258
            .:|::|..:.:||||:||||.|.|.:..|||.:||.|:...:|.:|..|||.|.||.||.:...|
 Frog   192 LVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVN 256

  Fly   259 LVPYPRIHFPLATYAPVISVEKAYHEQLTVAEITNACFEPANQMVKCDPRRGKYMACCMLYRGDV 323
            :||:||:||.:..:||:.|.....:..|||.|:|...|:..|.|..||||.|:|:....::||.:
 Frog   257 MVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRM 321

  Fly   324 VPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAW 388
            ..|:|:..:..::.|.|..||:|.|...|..:...||        ..::.:...:.|:|||.|.:
 Frog   322 SMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMSATFIGNSTAIQELF 378

  Fly   389 ARLDHKFDLMYAKRAFVHWYVGEGMEEGEFAEAREDLAALEKDYEEVGIDSTTELGEDEE 448
            .|:..:|..|:.::||:|||.||||:|.||.||..::..|..:|::....:..|.||.||
 Frog   379 KRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEE 438

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alphaTub85ENP_524297.1 PTZ00335 1..448 CDD:185562 180/448 (40%)
tubb2bNP_989275.1 PLN00220 1..430 CDD:215107 177/440 (40%)

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