Protein Alignment alphaTub85E and Tubb4a

DIOPT Version :10

• Sequence 1: NP_524297.1
• Gene: alphaTub85E / 41183
• FlyBaseID: FBgn0003886
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_543158.1
• Gene: Tubb4a / 29213
• RGDID: 619730
• Length: 444
• Species: Rattus norvegicus
• Alignment Length: 450
• Identity: 185/450 - (41%)
• Similarity: 273/450 - (60%)
• Gaps: 15/450 - (3%)

  Fly     1 MRECISVHIGQAGVQIGNACWELYCLEHGIQPDG--HMPSDKTVGGGDDSFSTFFSETGAGKHVP 63
            |||.:.:..||.|.|||...||:...||||.|.|  |..||..:    :..:.:::|...|.:||
  Rat     1 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQL----ERINVYYNEATGGNYVP 61

  Fly    64 RAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDVVLDRIRKLADQ 128
            |||.|||||..:|.||:|.:.|:|.|:..:.|:..|.||:|:||||.|.|:||.|||.:||.|:.
  Rat    62 RAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAES 126

  Fly   129 CTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHT 193
            |..||||.:.||.|||||||..:||:.::..::..:....||:.|:|:||..||||||:.|:.|.
  Rat   127 CDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQ 191

  Fly   194 TLEHSDCAFMVDNEAIYDICRRNLDIERPTYMNLNRLIGQIVSSITASLRFDGALNVDLTEFQTN 258
            .:|::|..:.:||||:||||.|.|.:..|||.:||.|:...:|.:|..|||.|.||.||.:...|
  Rat   192 LVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVN 256

  Fly   259 LVPYPRIHFPLATYAPVISVEKAYHEQLTVAEITNACFEPANQMVKCDPRRGKYMACCMLYRGDV 323
            :||:||:||.:..:||:.|.....:..|||.|:|...|:..|.|..||||.|:|:....::||.:
  Rat   257 MVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRM 321

  Fly   324 VPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAW 388
            ..|:|:..:.::::|.|..||:|.|...|..:...||        ..::.|...:.|:|||.|.:
  Rat   322 SMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMAATFIGNSTAIQELF 378

  Fly   389 ARLDHKFDLMYAKRAFVHWYVGEGMEEGEFAEAREDLAALEKDYEEVGIDSTTELGEDEE 448
            .|:..:|..|:.::||:|||.||||:|.||.||..::..|..:|::.. |:|.|.||.||
  Rat   379 KRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQ-DATAEEGEFEE 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub85E	NP_524297.1	PTZ00335	1..448	CDD:185562	183/448 (41%)
Tubb4a	NP_543158.1	PLN00220	1..427	CDD:215107	178/438 (41%)