Protein Alignment alphaTub85E and Tubb5

DIOPT Version :10

• Sequence 1: NP_524297.1
• Gene: alphaTub85E / 41183
• FlyBaseID: FBgn0003886
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_035785.1
• Gene: Tubb5 / 22154
• MGIID: 107812
• Length: 444
• Species: Mus musculus
• Alignment Length: 451
• Identity: 187/451 - (41%)
• Similarity: 274/451 - (60%)
• Gaps: 17/451 - (3%)

  Fly     1 MRECISVHIGQAGVQIGNACWELYCLEHGIQPDG--HMPSDKTVGGGDDSFSTFFSETGAGKHVP 63
            |||.:.:..||.|.|||...||:...||||.|.|  |..||..:    |..|.:::|...||:||
Mouse     1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQL----DRISVYYNEATGGKYVP 61

  Fly    64 RAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDVVLDRIRKLADQ 128
            ||:.|||||..:|.||:|.:.|:|.|:..:.|:..|.||:|:||||.|.|:||.|||.:||.|:.
Mouse    62 RAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAES 126

  Fly   129 CTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHT 193
            |..||||.:.||.|||||||..:||:.::..:|..:....||:.|:|:||..||||||:.|:.|.
Mouse   127 CDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQ 191

  Fly   194 TLEHSDCAFMVDNEAIYDICRRNLDIERPTYMNLNRLIGQIVSSITASLRFDGALNVDLTEFQTN 258
            .:|::|..:.:||||:||||.|.|.:..|||.:||.|:...:|.:|..|||.|.||.||.:...|
Mouse   192 LVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVN 256

  Fly   259 LVPYPRIHFPLATYAPVISVEKAYHEQLTVAEITNACFEPANQMVKCDPRRGKYMACCMLYRGDV 323
            :||:||:||.:..:||:.|.....:..|||.|:|...|:..|.|..||||.|:|:....::||.:
Mouse   257 MVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRM 321

  Fly   324 VPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAW 388
            ..|:|:..:..::.|.|..||:|.|...|..:...||        ..::.||..:.|:|||.|.:
Mouse   322 SMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMAVTFIGNSTAIQELF 378

  Fly   389 ARLDHKFDLMYAKRAFVHWYVGEGMEEGEFAEAREDLAALEKDYEEVGIDSTTELGEDEEY 449
            .|:..:|..|:.::||:|||.||||:|.||.||..::..|..:|::.. |:|.|  |:|::
Mouse   379 KRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQ-DATAE--EEEDF 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub85E	NP_524297.1	PTZ00335	1..448	CDD:185562	186/448 (42%)
Tubb5	NP_035785.1	PLN00220	1..429	CDD:215107	183/440 (42%)
		MREI motif. /evidence=ECO:0000250|UniProtKB:P07437	1..4		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	423..444		5/17 (29%)