Protein Alignment alphaTub85E and Tubb3

DIOPT Version :9

• Sequence 1: NP_524297.1
• Gene: alphaTub85E / 41183
• FlyBaseID: FBgn0003886
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_075768.1
• Gene: Tubb3 / 22152
• MGIID: 107813
• Length: 450
• Species: Mus musculus
• Alignment Length: 456
• Identity: 186/456 - (40%)
• Similarity: 272/456 - (59%)
• Gaps: 21/456 - (4%)

  Fly     1 MRECISVHIGQAGVQIGNACWELYCLEHGIQPDGHMPSDKTVGGGD---DSFSTFFSETGAGKHV 62
            |||.:.:..||.|.|||...||:...||||.|.|:.     ||..|   :..|.:::|..:.|:|
Mouse     1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNY-----VGDSDLQLERISVYYNEASSHKYV 60

  Fly    63 PRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDVVLDRIRKLAD 127
            |||:.|||||..:|.||:|.:..||.|:..|.|:..|.||:|:||||.|.|:||.|||.:||..:
Mouse    61 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKECE 125

  Fly   128 QCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTH 192
            .|..||||.:.||.|||||||..:||:.::..:|..:....||:.|:|:||..||||||:.|:.|
Mouse   126 NCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSIH 190

  Fly   193 TTLEHSDCAFMVDNEAIYDICRRNLDIERPTYMNLNRLIGQIVSSITASLRFDGALNVDLTEFQT 257
            ..:|::|..:.:||||:||||.|.|.:..|||.:||.|:...:|.:|.||||.|.||.||.:...
Mouse   191 QLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAV 255

  Fly   258 NLVPYPRIHFPLATYAPVISVEKAYHEQLTVAEITNACFEPANQMVKCDPRRGKYMACCMLYRGD 322
            |:||:||:||.:..:||:.:.....:..|||.|:|...|:..|.|..||||.|:|:....::||.
Mouse   256 NMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVATVFRGR 320

  Fly   323 VVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEA 387
            :..|:|:..:..|::|.|..||:|.|...||.:...||        ..::.:...:.|:|||.|.
Mouse   321 MSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPP--------RGLKMSSTFIGNSTAIQEL 377

  Fly   388 WARLDHKFDLMYAKRAFVHWYVGEGMEEGEFAEAREDLAALEKDYEEVGIDSTTELGE-----DE 447
            :.|:..:|..|:.::||:|||.||||:|.||.||..::..|..:|::....:..|.||     ||
Mouse   378 FKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEMYEDDDE 442

  Fly   448 E 448
            |
Mouse   443 E 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub85E	NP_524297.1	PTZ00335	1..448	CDD:185562	184/454 (41%)
Tubb3	NP_075768.1	PLN00220	1..447	CDD:215107	186/456 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	422..450		7/22 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900