Protein Alignment alphaTub85E and tbb-6

DIOPT Version :10

• Sequence 1: NP_524297.1
• Gene: alphaTub85E / 41183
• FlyBaseID: FBgn0003886
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_506075.2
• Gene: tbb-6 / 179680
• WormBaseID: WBGene00006539
• Length: 426
• Species: Caenorhabditis elegans
• Alignment Length: 439
• Identity: 157/439 - (35%)
• Similarity: 245/439 - (55%)
• Gaps: 20/439 - (4%)

  Fly     1 MRECISVHIGQAGVQIGNACWELYCLEHGIQPDGHMPSDKTVGGGDDSFSTFFSETGAGKHVPRA 65
            |:|.|:|.:||.|.|||...||....|||:|.||....|.  |...:..::::.|....|:||||
 Worm     1 MKEIINVQVGQCGNQIGAKFWEYISEEHGLQTDGTYKGDN--GSQLERITSYYKEMEGRKYVPRA 63

  Fly    66 VFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDVVLDRIRKLADQCT 130
            :.|||:|..::.||:..|.:||.||..::|:..|.||::||:|..|.||||.||..||:.|:...
 Worm    64 ILVDLDPESINYVRSTQYGKLFDPENAVSGESGAGNNWSRGYYEQGAEIVDKVLSVIRREAEAAD 128

  Fly   131 GLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTL 195
            .|:||.:.||.|||||||..|||:.:|..:|..|:....||.|:.:||..||||||:||:....:
 Worm   129 SLEGFQLIHSLGGGTGSGLGSLLISKLREEYSDKTLSTCSIIPSAKVSDTVVEPYNAILSMPHLM 193

  Fly   196 EHSDCAFMVDNEAIYDICRRNLDIE-RPTYMNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNL 259
            ::.|..|.:|||||:|||:.||.:| |.||.:||.|....:|.||...||.|.|..|:.:.  |.
 Worm   194 DNCDENFCIDNEAIFDICQYNLKLENRVTYGDLNHLASLALSGITTFQRFKGNLKTDIRKL--NT 256

  Fly   260 VPYPRIHFPLATYAPVISVEKAYHEQLTVAEITNACFEPANQMVKCDPRRGKYMACCMLYRGDVV 324
            ...||:||.:.::|||........:..:::::|....:..|.|. |:..:||:::..::|||...
 Worm   257 AGSPRLHFFMTSFAPVYGKGIIDCQAFSISDLTQQVLDAKNIMT-CNHNQGKFLSSAIIYRGQQT 320

  Fly   325 PKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWA 389
            .|.....|.:::.:...:.::..|......:     ..:|...|   :.:...::|:|||.|...
 Worm   321 EKKDAEQIISVENEDPSEMIESLPKSTNTDV-----CDIPSRGL---KTSATFIANSTAIQEPLK 377

  Fly   390 RLDHKFDLMYAKRAFVHWYVGEGMEEGEFAEAR---EDLAALEKDYEEV 435
            |:..:|..::.::||:|||.   |||.||.:|.   .||.:..:.||:|
 Worm   378 RISKQFAGLFRRKAFLHWYT---MEESEFTDAENKVNDLISEFQQYEKV 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub85E	NP_524297.1	PTZ00335	1..448	CDD:185562	157/439 (36%)
tbb-6	NP_506075.2	beta_tubulin	2..421	CDD:276956	153/434 (35%)