Protein Alignment alphaTub85E and tbb-1

DIOPT Version :10

• Sequence 1: NP_524297.1
• Gene: alphaTub85E / 41183
• FlyBaseID: FBgn0003886
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_499367.1
• Gene: tbb-1 / 176501
• WormBaseID: WBGene00006536
• Length: 449
• Species: Caenorhabditis elegans
• Alignment Length: 460
• Identity: 189/460 - (41%)
• Similarity: 274/460 - (59%)
• Gaps: 26/460 - (5%)

  Fly     1 MRECISVHIGQAGVQIGNACWELYCLEHGIQPDGHMPSDKTVGGGDD----SFSTFFSETGAGKH 61
            |||.:.|..||.|.|||:..||:...||||||||      |..|..|    ....:::|...||:
 Worm     1 MREIVHVQAGQCGNQIGSKFWEVISDEHGIQPDG------TFKGESDLQLERIDVYYNEANNGKY 59

  Fly    62 VPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDVVLDRIRKLA 126
            |||||.|||||..:|.||:|.:.|||.|:..:.|:..|.||:|:||||.|.|:||.|||.|||.|
 Worm    60 VPRAVLVDLEPGTMDSVRSGPFGQLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDNVLDVIRKEA 124

  Fly   127 DQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTT 191
            :.|..||||.:.||.|||||||..:||:.::..::..:....||:.|:|:||..||||||:.|:.
 Worm   125 EGCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMSSFSVVPSPKVSDTVVEPYNATLSV 189

  Fly   192 HTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYMNLNRLIGQIVSSITASLRFDGALNVDLTEFQ 256
            |..:|::|..:.:||||:||||.|.|.:..|||.:||.|:...:|.:|..|||.|.||.||.:..
 Worm   190 HQLVENTDETYCIDNEALYDICYRTLKLTNPTYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLA 254

  Fly   257 TNLVPYPRIHFPLATYAPVISVEKAYHEQLTVAEITNACFEPANQMVKCDPRRGKYMACCMLYRG 321
            .|:||:||:||.:..:||:.:.....:..|||||:|...|:..|.|..||||.|:|:....::||
 Worm   255 VNMVPFPRLHFFMPGFAPLSAKGAQAYRALTVAELTQQMFDAKNMMAACDPRHGRYLTVAAMFRG 319

  Fly   322 DVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAE 386
            .:..::|:..:.:::.|.|..||:|.|...|..:...||        ..::.|...:.|:|||.|
 Worm   320 RMSMREVDEQMLSVQNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMAATFVGNSTAIQE 376

  Fly   387 AWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFAEAREDLAALEKDYEEVGIDSTTE-------LG 444
            .:.|:..:|..|:.::||:|||.||||:|.||.||..::..|..:|::.. ::|.|       .|
 Worm   377 LFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLISEYQQYQ-EATAEDEPLDEFAG 440

  Fly   445 EDEEY 449
            |.|.|
 Worm   441 EGETY 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub85E	NP_524297.1	PTZ00335	1..448	CDD:185562	187/457 (41%)
tbb-1	NP_499367.1	PLN00220	1..447	CDD:215107	189/460 (41%)