Protein Alignment alphaTub85E and tbg-1

DIOPT Version :10

• Sequence 1: NP_524297.1
• Gene: alphaTub85E / 41183
• FlyBaseID: FBgn0003886
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_499131.1
• Gene: tbg-1 / 176361
• WormBaseID: WBGene00006540
• Length: 444
• Species: Caenorhabditis elegans
• Alignment Length: 456
• Identity: 125/456 - (27%)
• Similarity: 225/456 - (49%)
• Gaps: 42/456 - (9%)

  Fly     5 ISVHIGQAGVQIGNACWELYCLEHGIQPDGHMPSDKTVGGGDDSFSTFFSETGAGKHVPRAVFVD 69
            ::||:||.|.|:..|.|:....||||...|....:..:   :|.....|.:.....:|||||.||
 Worm     8 MTVHVGQCGNQLAQAFWKSMVDEHGINERGQTTHEDDM---NDKKDLLFYQADDDHYVPRAVLVD 69

  Fly    70 LEPTVVD-EVRTGTYRQLFHPEQLITGKE--DAANNYARGHYTIGKEIVDVVLDRIRKLADQCTG 131
            |||.|:: .:::..:..||:.:.:.....  .|.||:|.| |..|:|:.:.::|.|.:.|:....
 Worm    70 LEPRVINGMMQSPNFSNLFNTDNIFMSDHGGGAGNNWASG-YCQGQEVQEKIMDIIIREAENTNN 133

  Fly   132 LQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVST-AVVEPYNSILTTHTTL 195
            |.|.|..||..||||||..|||:|||...:.||....:|::.....|| .||.|||.:|:....:
 Worm   134 LDGILFTHSVSGGTGSGTGSLLLERLREAFPKKVIQTYSVFANSDTSTDVVVHPYNWVLSMQRLI 198

  Fly   196 EHSDCAFMVDNEAIYDICRRNLDIERPTYMNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLV 260
            |:.|...::||.|::.:.......:.||:.::|.|:.:|:|:.||..||:.|:...:.  ..:|.
 Worm   199 ENPDHVVVLDNAALHRLAAGKFKTDTPTFDHINSLVARIMSTSTAPYRFNSAMCPSIR--YLDLA 261

  Fly   261 PYPRIHFPLATYAPVISVEKAYHEQLTVAEITNACFEPANQMVKCDPR---RGKYMACCMLYRGD 322
            |:|.:||..:..:||:...:.:..:.:||::|....:|.:.||....|   ....::..|..:|.
 Worm   262 PFPPMHFIQSAISPVVDPNENFTRKTSVADVTRFLLKPTSMMVSTASRVRPNDCMLSAYMFLQGQ 326

  Fly   323 VVPKDVNAAIATIKTKRSIQFVDWCPTGF---KVGINYQP--PTVVPGGDLAKVQRAVCMLSNTT 382
            :....:..|      ::::.|....|..:   .:.:.:.|  |.|.|     :.:.:..:|:|:|
 Worm   327 IEAHTIMTA------EQNVDFAIRRPPFYMLKPLRMMHAPLSPYVRP-----QYKVSGLLLNNST 380

  Fly   383 AIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEE------GEFAEAREDL-----AALEKDYEEVG 436
            ::|..:..|..|:|.:.:||||:..:  |.::.      .:.....:||     |.::|||...|
 Worm   381 SVAPLFESLLSKYDKLRSKRAFIDKF--EKIDNFSLDMMDDAMHIVQDLLDEYKAVVQKDYLTRG 443

  Fly   437 I 437
            :
 Worm   444 L 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub85E	NP_524297.1	PTZ00335	1..448	CDD:185562	125/456 (27%)
tbg-1	NP_499131.1	gamma_tubulin	5..431	CDD:276957	120/441 (27%)