Protein Alignment alphaTub85E and tube1

DIOPT Version :10

• Sequence 1: NP_524297.1
• Gene: alphaTub85E / 41183
• FlyBaseID: FBgn0003886
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_001016136.1
• Gene: tube1 / 100488997
• XenbaseID: XB-GENE-492734
• Length: 472
• Species: Xenopus tropicalis
• Alignment Length: 475
• Identity: 141/475 - (29%)
• Similarity: 241/475 - (50%)
• Gaps: 60/475 - (12%)

  Fly     1 MRECISVHIGQAGVQIGNACWELYCLEHGIQPDGHMPSDKTVGGGDDSFSTFF------SETGA- 58
            |.:.|.|.:||.|.|||...|:|...||.        |....|..|::..:||      :|.|.
 Frog     1 MTQSIVVQVGQCGNQIGCRFWDLALREHA--------SVNKKGIFDEALCSFFRNVDTRAEAGGA 57

  Fly    59 ----GKHV---PRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVD 116
                ||..   .|||.:|:|..||:|:..|..|.||..:||||....:.||:|.||...|.:..:
 Frog    58 DAQRGKICSLKARAVLIDMEEGVVNEILQGPLRDLFDSKQLITDVSGSGNNWAVGHKLYGGQYRE 122

  Fly   117 VVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAV 181
            .:::.:|:.|:||..||.|.|.||.|||||||..:.::..|..::.:..:...|:||:.: ...:
 Frog   123 HIVENLRRTAEQCDCLQCFFVIHSMGGGTGSGLGTFVLNVLEEEFPEVYRFVTSVYPSAE-DDVI 186

  Fly   182 VEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRR-----------NL--------------DIER 221
            ..||||:|......||:||...::|:|:.||..:           |:              :.|:
 Frog   187 TSPYNSVLAMKELTEHADCVLPIENQALVDIVNKINQMANTGKLGNVKSNSLLTSNKGGIKENEK 251

  Fly   222 PTYMNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISVEKAYHEQL 286
            | :..:|.::..::.::|:|.||:|:||:||.|...||||:|::|:..::..|:.::........
 Frog   252 P-FDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLHYLTSSLTPLYTLADVNVPTR 315

  Fly   287 TVAEITNACFEPANQMVKCDPRRGKYMACCMLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGF 351
            .:.::.:..|...:|:::.||:...|:||.::.||:|...|:...|..:|.  .:|||.|...|:
 Frog   316 RLDQMFSDAFSKDHQLIRADPKHSLYLACALMVRGNVQISDLRRNIERLKP--FLQFVSWNQEGW 378

  Fly   352 KVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVG-EGMEE 415
            |.|:...||.    |.    ..::..|:|.|.:...:..|..:|..:|.|:|.:|.|:. :|||:
 Frog   379 KTGLCSVPPV----GH----SHSLLALANNTCVKPTFIELRDRFSKLYRKKAHLHHYMQVDGMEQ 435

  Fly   416 GEFAEAREDLAALEKDYEEV 435
            ..|.||...|::|.::|.::
 Frog   436 HCFTEAISSLSSLIEEYSQL 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub85E	NP_524297.1	PTZ00335	1..448	CDD:185562	141/475 (30%)
tube1	NP_001016136.1	epsilon_tubulin	2..455	CDD:276959	140/472 (30%)