Protein Alignment FoxP and foxp4

DIOPT Version :10

• Sequence 1: NP_001247011.1
• Gene: FoxP / 41182
• FlyBaseID: FBgn0262477
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001070655.1
• Gene: foxp4 / 768088
• XenbaseID: XB-GENE-982692
• Length: 645
• Species: Xenopus tropicalis
• Alignment Length: 398
• Identity: 162/398 - (40%)
• Similarity: 205/398 - (51%)
• Gaps: 97/398 - (24%)

  Fly    73 SSIDESSTAAQQHESNPHMHIQGQHMM--------------APVPDLGFYNVPEFISEQE----- 118
            ||:.....|.|| :......:|.||::              .|:|   ..::|:.:|..:
 Frog   158 SSLGNKQLAFQQ-QLLQMQQLQQQHLLNLQRQNLVGLQSGQGPLP---IQSLPQAVSPSDLQQLL 218

  Fly   119 KLMFSDAERFLRSKDNEV-----------------------CNNDFSYMHDEFAMRKYYHPLFAH 160
            |.|.|:.|.  .||.:.|                       ..|..:...|..:..:..|||:.|
 Frog   219 KEMSSNQEE--SSKQDTVDLTTSITTSFPNSKVSLPTIHPSLPNGQNTRRDSMSHYESSHPLYGH 281

  Fly   161 GICRWPGCEMDLEDITSFVKHLNTEHGLDDRSTAQARVQMQVVSQLESHLQKERDRLQAMMHHLY 225
            |.|||||||...||:..|:|||||||.||||||||.|||||||.|||..|.||.:||||||.||:
 Frog   282 GECRWPGCEALCEDMGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLEIQLAKESERLQAMMTHLH 346

  Fly   226 L------------------SKQLLSP-TKIDRKDVPGREGKFCRSPLTVNSIGRPIRQ-TNSPSP 270
            :                  |...:|| |..|....|...   ..:|:|      |:|| |:..|.
 Frog   347 MRPSEPKPFSQPLNLVSSASHNKMSPDTFPDGLPQPPTS---ATAPIT------PLRQGTSVISS 402

  Fly   271 LNLPMVNSTNLCSIKKRNHDKNTFSINGGLPYMLERAGLDVQQEIHRNREFYKNADVRPPFTYAS 335
            .:||.|.     .:::|..||  ||             ..:..|:.:|.||||||:|||||||||
 Frog   403 SSLPSVG-----PVRRRIVDK--FS-------------TPISSELAQNHEFYKNAEVRPPFTYAS 447

  Fly   336 LIRQAIIDSPDKQLTLNEIYNWFQNTFCYFRRNAATWKNAIRTNLSLHKCFVRYEDDFGSFWMVD 400
            ||||||:|:||:|||||||||||...|.|||||.||||||:|.||||||||||.|:..|:.|.||
 Frog   448 LIRQAILDTPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKGAVWTVD 512

  Fly   401 DNEFVKRR 408
            :.|:.|||
 Frog   513 ELEYQKRR 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxP	NP_001247011.1	FOXP-CC	157..224	CDD:465036	47/66 (71%)
		FH_FOX	327..408	CDD:469596	59/80 (74%)
foxp4	NP_001070655.1	FOXP-CC	278..345	CDD:465036	47/66 (71%)
		COG5025	<436..641	CDD:227358	63/85 (74%)
		FH_FOXP4	440..526	CDD:410841	60/81 (74%)