Protein Alignment FoxP and Foxp4

DIOPT Version :9

• Sequence 1: NP_001247011.1
• Gene: FoxP / 41182
• FlyBaseID: FBgn0262477
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: XP_017173175.1
• Gene: Foxp4 / 74123
• MGIID: 1921373
• Length: 692
• Species: Mus musculus
• Alignment Length: 371
• Identity: 162/371 - (43%)
• Similarity: 201/371 - (54%)
• Gaps: 68/371 - (18%)

  Fly   155 HPLFAHGICRWPGCEMDLEDITSFVKHLNTEHGLDDRSTAQARVQMQVVSQLESHLQKERDRLQA 219
            |||:.||.|:|||||...||:..|:|||||||.||||||||.|||||||.|||..|.||.:||||
Mouse   307 HPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLEIQLAKESERLQA 371

  Fly   220 MMHHLYLS-------KQLLSPTKIDRKDVPGREGKFCRSPLTVNSIGRPIRQTNSP-------SP 270
            ||.||::.       .|...|.......||| ...|  |.:||::...|....:.|       :|
Mouse   372 MMAHLHMRPSEPKPFSQPHLPHCSQLNPVPG-SSSF--SKVTVSADPFPDGLVHPPTSAAAPVTP 433

  Fly   271 LNLPMVNSTNLCS---IKKRNHDKNTFSINGGLPYMLERAGLDVQQEIHRNREFYKNADVRPPFT 332
            |..|.:.|.:|.|   .::|::||....|:               .|:.:|.|||||||||||||
Mouse   434 LRPPGLGSASLHSGGPARRRSNDKFCSPIS---------------SELAQNHEFYKNADVRPPFT 483

  Fly   333 YASLIRQAIIDSPDKQLTLNEIYNWFQNTFCYFRRNAATWKNAIRTNLSLHKCFVRYEDDFGSFW 397
            |||||||||:::||:|||||||||||...|.|||||.||||||:|.||||||||||.|:..|:.|
Mouse   484 YASLIRQAILETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKGAVW 548

  Fly   398 MVDDNEFVKRRHLSRGRPRKYEPS-----------------SSPNSCQSGNGVPTDKNPCDNCTQ 445
            .||:.|:.||      ||.|...|                 :|..:..:.:..|...||
Mouse   549 TVDEREYQKR------RPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLSNP------ 601

  Fly   446 HCTSLPPGADNPLDSNNPNDLGRIG-CLPYCGSDGLSKAS-KDYSN 489
              ..|.||:.:.|...:..|||..| .||..||....:.| ..||:
Mouse   602 --GMLNPGSASSLLPLSQEDLGVPGEPLPSNGSSSPPRLSPPQYSH 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxP	NP_001247011.1	FOXP-CC	157..224	CDD:292777	46/66 (70%)
		FH	328..400	CDD:238016	53/71 (75%)
Foxp4	XP_017173175.1	FOXP-CC	309..376	CDD:374402	46/66 (70%)
		COG5025	<375..>572	CDD:227358	95/220 (43%)
		FH	479..551	CDD:214627	53/71 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	126	1.000	Domainoid score	I5382
eggNOG	1	0.900	-	-		E2759_KOG4385
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001519
OrthoInspector	1	1.000	-	-		otm43440
orthoMCL	1	0.900	-	-		OOG6_103982
Panther	1	1.100	-	-	O	PTHR45796
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4064
SonicParanoid	1	1.000	-	-		X957
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.800