DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxP and fd96Ca

DIOPT Version :9

Sequence 1:	NP_001247011.1	Gene:	FoxP / 41182	FlyBaseID:	FBgn0262477	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001287516.1	Gene:	fd96Ca / 43010	FlyBaseID:	FBgn0004897	Length:	372	Species:	Drosophila melanogaster

Alignment Length:	221	Identity:	57/221 - (25%)
Similarity:	94/221 - (42%)	Gaps:	70/221 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   318 NREFYKNADVRPPFTYASLIRQAIIDSPDKQLTLNEIYNWFQNTFCYFRRNAATWKNAIRTNLSL 382
            :||.|  .:.:||::|.||...||..||:|.|.|::||.:..:.|.|:|:|...|:|::|.|||.
  Fly     5 SRESY--GEQKPPYSYISLTAMAIWSSPEKMLPLSDIYKFITDRFPYYRKNTQRWQNSLRHNLSF 67

  Fly   383 HKCFVRY-----EDDFGSFW--------MVDDNEFVKRRHLSRGRPRKYEPSSSPNSCQSGNGVP 434
            :.||::.     ....|::|        |.::...::||       ::::
  Fly    68 NDCFIKVPRRPDRPGKGAYWALHPQAFDMFENGSLLRRR-------KRFK--------------- 110

  Fly   435 TDKNPCDNCTQHCTSLP----------PGAD----NPLDSNN----------------PNDLGRI 469
            ..||..|...:..|:|.          .|..    :|||.||                ||.||..
  Fly   111 LHKNDKDLLNEELTALANLNRFFFTTRNGGSAAHMSPLDMNNAAAMRLDPLPRSTAHMPNSLGPG 175

  Fly   470 GCLPYCGSDGLSKASKDYSNM-DSGM 494
            ..||:.....:|.|  |::|: |.|:
  Fly   176 VPLPHVMPASMSGA--DHTNLADMGL 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxP	NP_001247011.1	FOXP-CC	157..224	CDD:292777
FoxP	NP_001247011.1	FH	328..400	CDD:238016	29/84 (35%)
fd96Ca	NP_001287516.1	FH	13..101	CDD:214627	29/87 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445498
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840