DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxP and jumu

DIOPT Version :9

Sequence 1:	NP_001247011.1	Gene:	FoxP / 41182	FlyBaseID:	FBgn0262477	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_524302.1	Gene:	jumu / 41265	FlyBaseID:	FBgn0015396	Length:	719	Species:	Drosophila melanogaster

Alignment Length:	270	Identity:	66/270 - (24%)
Similarity:	103/270 - (38%)	Gaps:	72/270 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   257 SIGRPIRQTNSPSPLNLPMVNSTNLCSIKKRNHDKNTFSINGGLPYMLERAGLDVQQEIHRNREF 321
            |:|.|  .:.|.|..:.|:.|.:||.:|.    :.||.....||...|       ||::
  Fly   355 SLGSP--SSLSSSSASSPLGNVSNLVNIA----NNNTSGAGSGLVKPL-------QQKV------ 400

  Fly   322 YKNADV-----RPPFTYASLIRQAIIDSPDKQLTLNEIYNWFQNTFCYFRRNAATWKNAIRTNLS 381
             |...|     :|.::|:.||..|:.:|....|.::|||::....|.||....:.|||::|.|||
  Fly   401 -KLPPVGSPFPKPAYSYSCLIALALKNSRAGSLPVSEIYSFLCQHFPYFENAPSGWKNSVRHNLS 464

  Fly   382 LHKCFVRYEDDFGSFWMVDDNEFVKRRHLSRGRPRKYEPSSSPNSCQSGNGVPTDKNPCDNCTQH 446
            |:|||.:.|                 |..:.|..||        .|:.... |...|..|...|.
  Fly   465 LNKCFEKIE-----------------RPATNGNQRK--------GCRWAMN-PDRINKMDEEVQK 503

  Fly   447 CTSLPPGADNPLDSNNPNDLGRIGCLPYCGS-DGLSKASKDYSNMDSGM-------IESNSHLTI 503
            .:...|.|..             |.:.|... :.|.:....:.:.||.:       ||.:|.|..
  Fly   504 WSRKDPAAIR-------------GAMVYPQHLESLERGEMKHGSADSDVELDSQSEIEESSDLEE 555

  Fly   504 DEYSTNMYES 513
            .|:...|.::
  Fly   556 HEFEDTMVDA 565

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxP	NP_001247011.1	FOXP-CC	157..224	CDD:292777
FoxP	NP_001247011.1	FH	328..400	CDD:238016	25/71 (35%)
jumu	NP_524302.1	Forkhead	411..499	CDD:278670	32/113 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445493
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840