Protein Alignment FoxP and foxi2

DIOPT Version :10

• Sequence 1: NP_001247011.1
• Gene: FoxP / 41182
• FlyBaseID: FBgn0262477
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_944598.2
• Gene: foxi2 / 387256
• ZFINID: ZDB-GENE-031126-2
• Length: 383
• Species: Danio rerio
• Alignment Length: 289
• Identity: 84/289 - (29%)
• Similarity: 132/289 - (45%)
• Gaps: 65/289 - (22%)

  Fly   267 SPSP---LNLPMVNSTNLCSIKKRNHDKNTFSINGGLP--YMLER---------AGLDV------ 311
            :|:|   ||.|.|||::     ...|..|:.|.   :|  |..:|         ||.|:
Zfish    63 TPNPYLWLNGPGVNSSS-----SYIHGNNSPSF---IPPAYGSQRQYLSNSSGFAGPDLGWLSIA 119

  Fly   312 -QQEIHRNREFYKNADVRPPFTYASLIRQAIIDSPDKQLTLNEIYNWFQNTFCYFRRNAATWKNA 375
             |:|:.:.        ||||::|::||..||.::.:|:|||::||.:..:.|.:::::.|.|:|:
Zfish   120 SQEELLKL--------VRPPYSYSALIAMAIQNAHEKKLTLSQIYQYVADNFPFYKKSKAGWQNS 176

  Fly   376 IRTNLSLHKCF---VRYEDD--FGSFWMVDDN--EFVKRRHLSRGRPRKYEPSSSPNSCQSGNGV 433
            ||.||||:.||   .|.|||  .|::|.:|.|  :.....:..|.|.|:.:.|:..:|    |..
Zfish   177 IRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRSDSSTGVSS----NTK 237

  Fly   434 PTDK------NPCDNCTQHCTS-LPPGADNPLDSN---NPNDLGRIGCLP--YCGSDGLSKASKD 486
            |.|.      .|.|  :.|.|. ..|.||...||:   :|..|....|..  :.....|..:|..
Zfish   238 PEDDRQLAGIKPTD--SPHLTGPASPDADAATDSHKGASPAGLASAPCFNNFFNSMSALGSSSTP 300

  Fly   487 YSNMDS-GMIESNSHLTIDEYSTNMYESS 514
            .|...| |::...|...|...|.  |.:|
Zfish   301 TSRHGSLGLVNELSSRNISALSP--YHAS 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxP	NP_001247011.1	FOXP-CC	157..224	CDD:465036
		FH_FOX	327..408	CDD:469596	35/87 (40%)
foxi2	NP_944598.2	COG5025	<8..>207	CDD:227358	52/159 (33%)
		FH_FOX	126..218	CDD:469596	35/99 (35%)
		COG5025	130..>338	CDD:227358	63/206 (31%)