Protein Alignment FoxP and foxa3

DIOPT Version :10

• Sequence 1: NP_001247011.1
• Gene: FoxP / 41182
• FlyBaseID: FBgn0262477
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_571374.1
• Gene: foxa3 / 30559
• ZFINID: ZDB-GENE-980526-423
• Length: 441
• Species: Danio rerio
• Alignment Length: 346
• Identity: 88/346 - (25%)
• Similarity: 133/346 - (38%)
• Gaps: 89/346 - (25%)

  Fly   230 LLSPTKIDRKDVP------GREGKFCRSPLTVNSI--------------------GRPIRQTNSP 268
            :||..|::..::|      ....:...||..:||:                    |.|....||
Zfish     1 MLSSVKMESHEIPEWNPFYSEANEMYSSPSAMNSVSSLNSYINLNSACSTSSMNMGYPSAGLNS- 64

  Fly   269 SPLN-----------LPMVNSTNLCSIKKRNHDKNTFSINGGLPYMLERAGLDVQQ-------EI 315
            |||:           .|:.:|.|..|:.:.....:|.   |.|.: .:..|..:.|       .:
Zfish    65 SPLSSMGGGPNHMSLSPVGSSLNPSSLTQLGSSASTL---GPLSH-YQSMGQPMSQISYPSPTSL 125

  Fly   316 HRNREF---YKNA--DVRPPFTYASLIRQAIIDSPDKQLTLNEIYNWFQNTFCYFRRNAATWKNA 375
            :|.:|.   |:.:  ..:||::|.|||..||..|..|.|||||||.|..:.|.|:|.|...|:|:
Zfish   126 NRTKEMPKPYRRSLTHAKPPYSYISLITMAIQQSQSKMLTLNEIYQWIMDLFPYYRENQQRWQNS 190

  Fly   376 IRTNLSLHKCFVRY-----EDDFGSFWMVDDNE---FVKRRHLSRGRPRKY-EPSSSPNSCQSGN 431
            ||.:||.:.|||:.     :...||:|.:..|.   |....:|.|.:..|. |.:...:|.:|.:
Zfish   191 IRHSLSFNDCFVKVARSPDKPGKGSYWALHPNSGNMFENGCYLRRQKRFKIEEKAGKKSSSKSQD 255

  Fly   432 GVPTDKNPCDNCTQHCTSLPPGADNPLDSNNPNDLGRIGCLPYCGSDGLSKASKDYSNMDSGMIE 496
            |..|.........|...|                       |..||||...|..|.|:..|...|
Zfish   256 GSSTKGTHSSEGMQEEHS-----------------------PTTGSDGAESAHSDSSHAGSTSEE 297

  Fly   497 SNSHLT-ID--EYSTNMYESS 514
            ....|. :|  ..:.|:..||
Zfish   298 QQRSLVQLDCPSQAPNLLHSS 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxP	NP_001247011.1	FOXP-CC	157..224	CDD:465036
		FH_FOX	327..408	CDD:469596	36/88 (41%)
foxa3	NP_571374.1	Forkhead_N	17..142	CDD:369872	23/129 (18%)
		FH_FOXA3	141..242	CDD:410814	39/100 (39%)
		HNF_C	373..>408	CDD:430552