Protein Alignment FoxP and foxa1

DIOPT Version :10

• Sequence 1: NP_001247011.1
• Gene: FoxP / 41182
• FlyBaseID: FBgn0262477
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_571359.2
• Gene: foxa1 / 30541
• ZFINID: ZDB-GENE-990415-78
• Length: 427
• Species: Danio rerio
• Alignment Length: 303
• Identity: 81/303 - (26%)
• Similarity: 131/303 - (43%)
• Gaps: 64/303 - (21%)

  Fly   255 VNSIGRPIRQTNSPSPLNLPMVNSTNLCSIKKRNHDKNTFSINGGLPYMLERAGLDVQQEIHR-- 317
            |:|:|..:    |||.||......:::.::........|.|   .:.|        .|..::|
Zfish    95 VSSMGTAL----SPSNLNAMTAQHSSMNALNPYTSMSPTMS---SMTY--------AQPNLNRAR 144

  Fly   318 -NREF---YKNADVRPPFTYASLIRQAIIDSPDKQLTLNEIYNWFQNTFCYFRRNAATWKNAIRT 378
             |:.|   |.:|  :||::|.|||..||..:|.|.|||:|||.|..:.|.|:|:|...|:|:||.
Zfish   145 DNKTFRRSYPHA--KPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRH 207

  Fly   379 NLSLHKCFVRY-----EDDFGSFW--------MVDDNEFVKRR------------HLSRGRPRKY 418
            :||.:.|||:.     :...||:|        |.::..:::|:            ..|.|:..:.
Zfish   208 SLSFNDCFVKVSRSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFKCDKKLPDGKRSEGKREQS 272

  Fly   419 EPSSSPNSCQSGNGVPTDKNPCDNCTQHCTSLPPGADNPLDSNNPNDLGRIGCLPYCGSDGLSKA 483
            ..|.||.| .|.:..|...:.....:.:.:|.||..|:...|:..::|       ..|...:...
Zfish   273 SGSGSPAS-DSTSSKPVHMDSSSITSSNQSSSPPSLDHRSGSSANSEL-------KSGGPQVHPV 329

  Fly   484 SKDYSNMDSGMIESNSHLTID-EYS-------TNMYESSANEH 518
            |...|::.|...||..||..| .||       .|:..||..:|
Zfish   330 STSLSSLHSMAHESQLHLKGDPHYSFNHPFSINNLMSSSEQQH 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxP	NP_001247011.1	FOXP-CC	157..224	CDD:465036
		FH_FOX	327..408	CDD:469596	34/93 (37%)
foxa1	NP_571359.2	Forkhead_N	17..156	CDD:369872	16/75 (21%)
		FH_FOXA1	145..255	CDD:410812	39/111 (35%)
		HNF_C	356..416	CDD:430552	4/17 (24%)