Protein Alignment FoxP and Foxp1

DIOPT Version :10

• Sequence 1: NP_001247011.1
• Gene: FoxP / 41182
• FlyBaseID: FBgn0262477
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: XP_038963306.1
• Gene: Foxp1 / 297480
• RGDID: 1308669
• Length: 733
• Species: Rattus norvegicus
• Alignment Length: 478
• Identity: 174/478 - (36%)
• Similarity: 235/478 - (49%)
• Gaps: 135/478 - (28%)

  Fly    52 TGFLNNSITFASHVVKCSSPASSIDESSTAAQQHESNPHMHIQGQHMMAPVPDLGFYNVPEFISE 116
            ||..::|:...|..|..|:|      |.|:...   |||....|| :....|            :
  Rat   301 TGSNHSSLDLTSTCVSSSAP------SKTSLIM---NPHASTNGQ-LSVHTP------------K 343

  Fly   117 QEKLMFSDAERFLRSKDNEVCNNDFSYMHDEFAMRKYYHPLFAHGICRWPGCEMDLEDITSFVKH 181
            :|.|                       .|:|   ..:.|||:.||:|:|||||...:|..:|:||
  Rat   344 RESL-----------------------SHEE---HPHSHPLYGHGVCKWPGCEAVCDDFPAFLKH 382

  Fly   182 LNTEHGLDDRSTAQARVQMQVVSQLESHLQKERDRLQAMMHHLYLSKQLLSPTKIDRKDVPGREG 246
            ||:||.||||||||.|||||||.|||..|.|:::||||||.||:               |...|.
  Rat   383 LNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLH---------------VKSTEP 432

  Fly   247 KFCRSPLTVNSIGRPIRQTNSPSPLNLP------------------MVNSTNLCS---IKKRNHD 290
            |....||.:.|.....:..:..||.:||                  ::.:|::.:   |::|..|
  Rat   433 KAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSD 497

  Fly   291 KNTFSINGGLPYMLERAGLDVQQEIHRNREFYKNADVRPPFTYASLIRQAIIDSPDKQLTLNEIY 355
            |....|:..              :|.:|:||||||:|||||||||||||||::||:|||||||||
  Rat   498 KYNVPISSA--------------DIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIY 548

  Fly   356 NWFQNTFCYFRRNAATWKNAIRTNLSLHKCFVRYEDDFGSFWMVDDNEFVKRRHLSRGRPRKYEP 420
            |||...|.||||||||||||:|.||||||||||.|:..|:.|.||:.||.||      ||:|.
  Rat   549 NWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKR------RPQKI-- 605

  Fly   421 SSSPN---SCQSGNGVPTDKNPCDNCTQHCTSLPPG-----ADNPLDSNNPNDLGRIGCLPYCGS 477
            |.:|:   :.|||:.             :||.|...     |:|.:.......:|.    |..||
  Rat   606 SGNPSLIKNMQSGHA-------------YCTPLNAALQASMAENSIPLYTTASMGN----PTLGS 653

  Fly   478 DGLSKASKDYSNMDSGMIESNSH 500
              |:.|.::  .::..|..:||:
  Rat   654 --LASAIRE--ELNGAMEHTNSN 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxP	NP_001247011.1	FOXP-CC	157..224	CDD:465036	43/66 (65%)
		FH_FOX	327..408	CDD:469596	61/80 (76%)
Foxp1	XP_038963306.1	FOXP-CC	358..425	CDD:465036	43/66 (65%)
		COG5025	493..>707	CDD:227358	96/223 (43%)
		FH_FOXP2	520..601	CDD:410839	62/86 (72%)