Protein Alignment FoxP and Foxp1

DIOPT Version :10

• Sequence 1: NP_001247011.1
• Gene: FoxP / 41182
• FlyBaseID: FBgn0262477
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: XP_030110934.1
• Gene: Foxp1 / 108655
• MGIID: 1914004
• Length: 723
• Species: Mus musculus
• Alignment Length: 465
• Identity: 183/465 - (39%)
• Similarity: 241/465 - (51%)
• Gaps: 111/465 - (23%)

  Fly    69 SSPASSIDESST----AAQQHES---NPHMHIQGQHMMAPVPDLGFYNVPEFISEQEKLMFSDAE 126
            ||..||:|.:||    :|....|   |||....|| :....|            ::|.|
Mouse   276 SSNHSSLDLTSTCVSSSAPSKSSLIMNPHASTNGQ-LSVHTP------------KRESL------ 321

  Fly   127 RFLRSKDNEVCNNDFSYMHDEFAMRKYYHPLFAHGICRWPGCEMDLEDITSFVKHLNTEHGLDDR 191
                             .|:|   ..:.|||:.||:|:|||||...:|..:|:||||:||.||||
Mouse   322 -----------------SHEE---HPHSHPLYGHGVCKWPGCEAVCDDFPAFLKHLNSEHALDDR 366

  Fly   192 STAQARVQMQVVSQLESHLQKERDRLQAMMHHLYLSKQLLSPTKIDRKDVPGREGKFCRSPLTVN 256
            ||||.|||||||.|||..|.|:::||||||.||:               |...|.|....||.:.
Mouse   367 STAQCRVQMQVVQQLELQLAKDKERLQAMMTHLH---------------VKSTEPKAAPQPLNLV 416

  Fly   257 SIGRPIRQTNSPSPLNLP------------------MVNSTNLCS---IKKRNHDKNTFSINGGL 300
            |.....:..:..||.:||                  ::.:|::.:   |::|..||....|:..
Mouse   417 SSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSA- 480

  Fly   301 PYMLERAGLDVQQEIHRNREFYKNADVRPPFTYASLIRQAIIDSPDKQLTLNEIYNWFQNTFCYF 365
                         :|.:|:||||||:|||||||||||||||::||:||||||||||||...|.||
Mouse   481 -------------DIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYF 532

  Fly   366 RRNAATWKNAIRTNLSLHKCFVRYEDDFGSFWMVDDNEFVKRRHLSRGRPRKYEPSSSPNSCQSG 430
            ||||||||.||||||||||||:|.||:|||||.|||.||::.||:.|||||||.|..  ||.:.|
Mouse   533 RRNAATWKGAIRTNLSLHKCFIRVEDEFGSFWTVDDEEFIRGRHIQRGRPRKYCPGE--NSDELG 595

  Fly   431 NGVPTDKNPCDNCTQHCTSLPPG-----ADNPLDSNNPNDLGRIGCLPYCGSDGLSKASKDYSNM 490
            ...|:......:...:||.|...     |:|.:.......:|.    |..||  |:.|.::  .:
Mouse   596 AHNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGN----PTLGS--LASAIRE--EL 652

  Fly   491 DSGMIESNSH 500
            :..|..:||:
Mouse   653 NGAMEHTNSN 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxP	NP_001247011.1	FOXP-CC	157..224	CDD:465036	43/66 (65%)
		FH_FOX	327..408	CDD:469596	65/80 (81%)
Foxp1	XP_030110934.1	FOXP-CC	332..399	CDD:465036	43/66 (65%)
		FH_FOX	494..575	CDD:469596	65/80 (81%)