Protein Alignment FoxP and foxp2

DIOPT Version :9

• Sequence 1: NP_001247011.1
• Gene: FoxP / 41182
• FlyBaseID: FBgn0262477
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: XP_012813833.2
• Gene: foxp2 / 100101742
• XenbaseID: XB-GENE-482683
• Length: 744
• Species: Xenopus tropicalis
• Alignment Length: 365
• Identity: 155/365 - (42%)
• Similarity: 197/365 - (53%)
• Gaps: 63/365 - (17%)

  Fly   142 SYMHDEFAMRKYYHPLFAHGICRWPGCEMDLEDITSFVKHLNTEHGLDDRSTAQARVQMQVVSQL 206
            |..|:|....   |.|:.||:|:|||||...||...|:||||.||.||||||||.|||||||.||
 Frog   329 SSSHEETGAS---HTLYGHGVCKWPGCENICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQL 390

  Fly   207 ESHLQKERDRLQAMMHHLYLSK----------QLLSPTKIDRKDVPGREGKFCRSPLTVNSIGRP 261
            |..|.|||:||||||.||::..          .|:|...:.:..:........::|.|..:...|
 Frog   391 EIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSTVTMSKNMLETSPQSLPQTPTTPTAPVTP 455

  Fly   262 IRQTNSPS---PLNLPMVNSTNLCSIKKRNHDKNTFSINGGLPYMLERAGLDVQQEIHRNREFYK 323
            |.|  .||   |.::|     |:.:|::|:.||               ..:.:..||..|.||||
 Frog   456 IAQ--GPSVITPASVP-----NVGAIRRRHSDK---------------YNIPMSTEIAPNYEFYK 498

  Fly   324 NADVRPPFTYASLIRQAIIDSPDKQLTLNEIYNWFQNTFCYFRRNAATWKNAIRTNLSLHKCFVR 388
            |||||||||||:||||||::|.|:||||||||:||..||.||||||||||||:|.||||||||||
 Frog   499 NADVRPPFTYATLIRQAIMESGDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVR 563

  Fly   389 YEDDFGSFWMVDDNEFVKRRHLS-RGRPR--KYEPSS---------SPNSCQSGNGVPTDKNPCD 441
            .|:..|:.|.||:.|:.|||... .|.|.  |..|:|         |..:..:.:.:|...|
 Frog   564 VENVKGAVWTVDEAEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSN--- 625

  Fly   442 NCTQHCTSLPPG--------ADNPLDSNNPNDLGRIGCLP 473
              |....:..||        .:..||..:.|.....||.|
 Frog   626 --TGLLNNASPGLLQAVHEDLNGSLDHIDSNGNSSPGCSP 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxP	NP_001247011.1	FOXP-CC	157..224	CDD:292777	46/66 (70%)
		FH	328..400	CDD:238016	53/71 (75%)
foxp2	XP_012813833.2	FOXP-CC	341..408	CDD:406546	46/66 (70%)
		COG5025	476..>668	CDD:227358	90/208 (43%)
		FH_FOXP2	502..583	CDD:410839	58/80 (73%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	105	1.000	Domainoid score	I6553
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001519
OrthoInspector	1	1.000	-	-		otm48587
Panther	1	1.100	-	-	O	PTHR45796
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4064
SonicParanoid	1	1.000	-	-		X957
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.130