DRSC/TRiP Functional Genomics Resources

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Protein Alignment hyd and BAG3

DIOPT Version :9

Sequence 1:NP_001287262.1 Gene:hyd / 41181 FlyBaseID:FBgn0002431 Length:2887 Species:Drosophila melanogaster
Sequence 2:NP_004272.2 Gene:BAG3 / 9531 HGNCID:939 Length:575 Species:Homo sapiens


Alignment Length:234 Identity:56/234 - (23%)
Similarity:76/234 - (32%) Gaps:106/234 - (45%)


- Green bases have known domain annotations that are detailed below.


  Fly  1017 FATMSSSAAGSASSTSRDNRTNLRDMMNRLINSDQAEQ----SGSQPMATNNEDHAYIPWPAETP 1077
            |.|.:::||...|      ::.||.|........|..|    :.:||.|::.      |..:::|
Human   122 FRTEAAAAAPQRS------QSPLRGMPETTQPDKQCGQVAAAAAAQPPASHG------PERSQSP 174

  Fly  1078 AASNLSASSSQNVSDSIEDDISKIIPSSSQSSMLSNIKLGSPTYTFDLAQRREHAL--------T 1134
            |||:.|:|||           |..:|||.:||      |||            |.|        .
Human   175 AASDCSSSSS-----------SASLPSSGRSS------LGS------------HQLPRGYISIPV 210

  Fly  1135 ILQQMCVSPALRP----------------YLCHMLSTKDAQGQ----------TPFMLSVSCRAY 1173
            |.:|....||.:|                |..|.......||.          :||..||     
Human   211 IHEQNVTRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSV----- 270

  Fly  1174 EAGIILLNTILMLSEQDPQLKEAMIFPNGSPADQS-PLH 1211
                           |....:|      ||||..| |||
Human   271 ---------------QGASSRE------GSPARSSTPLH 288

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hydNP_001287262.1 E3_UbLigase_EDD 150..196 CDD:288409
ZnF_UBR1 1217..1284 CDD:197698
ASF1_hist_chap 1535..1733 CDD:304562
PolyA 2498..2561 CDD:197769
HECTc 2589..2885 CDD:238033
HECTc 2589..2884 CDD:214523
BAG3NP_004272.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..92
WW 21..53 CDD:197736
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 123..200 30/117 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 240..421 18/75 (24%)
BAG 421..498 CDD:214591
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 532..575
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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