DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trbd and Tnfaip3

DIOPT Version :9

Sequence 1:	NP_649931.1	Gene:	trbd / 41179	FlyBaseID:	FBgn0037734	Length:	778	Species:	Drosophila melanogaster
Sequence 2:	XP_038954753.1	Gene:	Tnfaip3 / 683206	RGDID:	1589275	Length:	814	Species:	Rattus norvegicus

Alignment Length:	365	Identity:	102/365 - (27%)
Similarity:	163/365 - (44%)	Gaps:	69/365 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   373 IAALNRNSAFDVGHTLIHLAIRFHREEMLPMLLDQISGSGPGIKRVPSYVAPDLAADIRRHFANT 437
            :.||:|..|                |::||..| .:|.....:|             ||......
  Rat    31 LQALSRTMA----------------EQLLPQAL-YLSNMRKAVK-------------IRERTPED 65

  Fly   438 LRLRKSGLPCHYVQKHA-TFALPAEIEELPIPIQEQLYDELLDRDAQKQLETPPPALNWSLEITA 501
            :....:|:..|:...|. |..:....:..| ..:|.::..|:||..|..||: ...|||..|:
  Rat    66 IFKPSNGIIHHFKTMHRYTLEMFRTCQFCP-QFREIIHKALIDRSVQASLES-QKKLNWCREV-- 126

  Fly   502 RLSSRMFVLWNRSAGDCLLDSAMQATWGVFDRDNILRRALADTLHQCG-HVFFTRW-----KEYE 560
               .::..|.....|:||:.:|.|..|||.|.|.:||:||..||.:.. ..|..||     |..|
  Rat   127 ---RKLVALKTNGDGNCLMHAACQYMWGVQDTDLVLRKALCSTLKETDTRNFKFRWQLESLKSQE 188

  Fly   561 MLQASMLHFTLEDSQFEEDWSTLLSLA---------GQPGSSLEQLHIFALAHILRRPIIVYGVK 616
            .::..:.:.|   ..:.::|..|:.:|         |...:|||::|||.|::||||||||...|
  Rat   189 FVETGLCYDT---RNWNDEWDNLVKMASADTPAARSGLQYNSLEEIHIFVLSNILRRPIIVISDK 250

  Fly   617 YVKSFR-GEDIGYARFEGVYLPLFWDQNFCTKSPIALGYTRGHFSALVPMEPFTRIDGRRDDVED 680
            .::|.. |.:....:..|:||||.|....|.:.||.|||...||..||.:         :|...:
  Rat   251 MLRSLESGSNFAPLKVGGIYLPLHWPAQECYRYPIVLGYDSQHFVPLVTL---------KDSGPE 306

  Fly   681 VTYLPLMDCE---LKLLPIHFLTQSEVGNEESMMRQWLDV 717
            :..:||::.|   .:.|.:||||..|...:|.:::::|.|
  Rat   307 IRAVPLVNRERGRFEDLKVHFLTDPEHEMKEKLLKEYLMV 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trbd	NP_649931.1	zf-RanBP	11..36	CDD:279035
		RanBP2-type Zn finger	11..30	CDD:275376
		ZnF_RBZ	91..114	CDD:197784
		RanBP2-type Zn finger	93..112	CDD:275376
		RanBP2-type Zn finger	175..192	CDD:275375
		ZnF_RBZ	234..256	CDD:197784
		RanBP2-type Zn finger	236..255	CDD:275376
		OTU	513..659	CDD:280496	56/161 (35%)
Tnfaip3	XP_038954753.1	OTU	135..294	CDD:396767	56/161 (35%)
		ZnF_A20	421..446	CDD:128555
		ZnF_A20	505..530	CDD:128555
		ZnF_A20	628..653	CDD:128555
		ZnF_A20	679..703	CDD:128555
		ZnF_A20	737..762	CDD:128555
		ZnF_A20	783..808	CDD:128555
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D319972at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13367
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020