DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trbd and Otud7b

DIOPT Version :9

Sequence 1:	NP_649931.1	Gene:	trbd / 41179	FlyBaseID:	FBgn0037734	Length:	778	Species:	Drosophila melanogaster
Sequence 2:	NP_001101167.1	Gene:	Otud7b / 310677	RGDID:	1308111	Length:	841	Species:	Rattus norvegicus

Alignment Length:	366	Identity:	103/366 - (28%)
Similarity:	168/366 - (45%)	Gaps:	82/366 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   464 ELP-IPIQEQLYDELLDRDAQKQ-----LETPPPALNW--SLEITARLSSRMFVLWNRSAGDCLL 520
            :|| :.:.::.:...::||..:|     || ....|||  |::.|.:   |:..|.....|:|||
  Rat   136 QLPDLTVYKEDFRSFIERDLIEQSMLVALE-QAGRLNWWVSVDSTCQ---RLLPLATTGDGNCLL 196

  Fly   521 DSAMQATWGVFDRDNILRRAL---------ADTLHQCGHVFFTRWKEYEMLQASMLHFTLEDSQF 576
            .:|....||..|||.:||:||         .:.|.:     ..||::.:..:.|.|.:|  :.::
  Rat   197 HAASLGMWGFHDRDLVLRKALYALMEKGVEKEALKR-----RWRWQQTQQNKESGLVYT--EDEW 254

  Fly   577 EEDWSTLLSLA-----------GQPG-----------SSLEQLHIFALAHILRRPIIVYGVKYVK 619
            :::|:.|:.||           |..|           .|||:.|:|.|||:|:|||:|.....::
  Rat   255 QKEWNELIKLASSEPRMHLGTNGASGGGVESSEEPVYESLEEFHVFVLAHVLKRPIVVVADTMLR 319

  Fly   620 SFRGEDIGYARFEGVYLPLFWDQNFCTKSPIALGYTRGHFSALVPMEPFTRIDGRRDDVEDVTYL 684
            ...||......|.|:||||....:.|.:||:.|.|.:.||||||.||       ::|..::...:
  Rat   320 DSGGEAFAPIPFGGIYLPLEVPASQCHRSPLVLAYDQAHFSALVSME-------QKDSAKEQAVI 377

  Fly   685 PLMDCELKLLPIHFLTQS----EVGNEESMMRQWLDVCVTDGGLLVAQQKLSKRPLLVAQMLEEW 745
            ||.|.|.||||:||....    |.|.:::...:...|      :|..:.||.   ||.:.|..:|
  Rat   378 PLTDSEHKLLPLHFAVDPGKGWEWGKDDNDNVRLASV------ILSLEVKLH---LLHSYMNVKW 433

  Fly   746 LNHYRRIAQVITAPFIRRPQITHYSSD--------GDSDEE 778
            :    .::....||..:....|..:.|        |:||:|
  Rat   434 I----PLSSESQAPLAQPESPTASAGDEPRSTPESGESDKE 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trbd	NP_649931.1	zf-RanBP	11..36	CDD:279035
		RanBP2-type Zn finger	11..30	CDD:275376
		ZnF_RBZ	91..114	CDD:197784
		RanBP2-type Zn finger	93..112	CDD:275376
		RanBP2-type Zn finger	175..192	CDD:275375
		ZnF_RBZ	234..256	CDD:197784
		RanBP2-type Zn finger	236..255	CDD:275376
		OTU	513..659	CDD:280496	52/176 (30%)
Otud7b	NP_001101167.1	UBA_Cezanne_like	4..46	CDD:270532
		OTU	189..359	CDD:303090	52/176 (30%)
		zf-A20	799..821	CDD:280010
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4345
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D319972at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820