Protein Alignment Unc-115b and Dmtn

DIOPT Version :10

• Sequence 1: NP_731390.1
• Gene: Unc-115b / 41178
• FlyBaseID: FBgn0260463
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_001381675.1
• Gene: Dmtn / 361069
• RGDID: 1311419
• Length: 405
• Species: Rattus norvegicus
• Alignment Length: 321
• Identity: 73/321 - (22%)
• Similarity: 115/321 - (35%)
• Gaps: 113/321 - (35%)

  Fly   434 TPLS--PHFHRPSSYATTASNAGSVAGSRPPSRPHSRTRSAMKVLVDAIRSETPRPKSPGMNNEE 496
            ||.:  ||||.|.:             :||.|..:.:     ..:.....|....|:|..:..:.
  Rat   120 TPRTSLPHFHHPET-------------TRPDSNIYKK-----PPIYKQRESVGGSPQSKHLIEDL 166

  Fly   497 PIELSHYPAAKKPPPGEQPKIERDDFPAPP-YPYTDPERRRRYSDTYKGVPASDDEDENVENGKP 560
            .||.|.:|||:.|.|.:..|||.|.:|.|| ....:.|.|:|.: :.||....::|:::
  Rat   167 IIESSKFPAAQPPDPNQPAKIETDYWPCPPSLAVVETEWRKRKA-SRKGAEEEEEEEDD------ 224

  Fly   561 NGKVKNGEEQQRL--QREAEQLEKLNSGIGSAIAKDLKEHAKYRKWKQNNLDPRNASRTPSASKE 623
                 :.||:.:.  :|:.|:|.|:.|.:|..|.|:..|.:                 .|...|
  Rat   225 -----DSEEEIKAIRERQKEELSKVTSNLGKMILKEEMEKS-----------------LPIRRK- 266

  Fly   624 PLYKLRYESPIGASPSRNLDHQKPFYEDEMFDRSTSYRGSLGKSLGNAPSYNAIHSYRSPPKPGY 688
                           :|:|..:.||:        ||......|| .:.|||.
  Rat   267 ---------------TRSLPDRTPFH--------TSLHSGTSKS-SSLPSYG------------- 294

  Fly   689 GFKTTTLPYIRNGFSSDFSYGGLGDKTHSTDLSCGKSEASVDSITEGD-RRALM--GGDLP 746
               .|||                 .:..||:.|...|||....:..|: :|..|  |..||
  Rat   295 ---RTTL-----------------SRLQSTEFSPSGSEAGSPGLQNGEGQRGRMDRGNSLP 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Unc-115b	NP_731390.1	LIM1_abLIM	46..97	CDD:188713
		LIM2_abLIM	102..157	CDD:188714
		LIM3_abLIM	211..262	CDD:188715
		LIM4_abLIM	270..326	CDD:188716
Dmtn	NP_001381675.1	AbLIM_anchor	8..355	CDD:465046	73/321 (23%)
		VHP	370..405	CDD:128458