Protein Alignment Unc-115b and Ablim1

DIOPT Version :9

• Sequence 1: NP_731390.1
• Gene: Unc-115b / 41178
• FlyBaseID: FBgn0260463
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_001382083.1
• Gene: Ablim1 / 307989
• RGDID: 1565768
• Length: 863
• Species: Rattus norvegicus
• Alignment Length: 940
• Identity: 275/940 - (29%)
• Similarity: 357/940 - (37%)
• Gaps: 360/940 - (38%)

  Fly     7 ISIPKHPQTDKTRP--------IYPSTLG-TELRTELGKT----------GQGKQKIYCAKCTKK 52
            :|:|:.|...:.|.        :|.|..| .|||.....:          ...|..|:|.||.:.
  Rat    42 LSVPETPHPARHRHGTVTYLFYLYSSNRGPPELRFSSCDSSVAHPQDPHHSSEKPVIHCHKCGEP 106

  Fly    53 CSGEVLRVADNHFHKACFQCCQCKKSLATGGFFTKDNAYYCIPDYQRLYGTKCANCQQYVEGEVV 117
            |.||||||...|||..||.|..|...||.||||.|:..|.|..||||:|||:|..|.::||||||
  Rat   107 CKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGDYLCTLDYQRMYGTRCHGCGEFVEGEVV 171

  Fly   118 STMGKTYHQKCFTCSKCKQPFKSGSKVTNTGKEVLCEQCVTGAPVSPSRQATGGGVSSPAPPAES 182
            :.:|||||..||.|:.||:||..|.:||..|::.||:.|.                   .|.:.|
  Rat   172 TALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCA-------------------QPMSSS 217

  Fly   183 PTRATAHQQHGSVISHKAHLKEDYDPNDCAGCGELLKEGQALVALDRQWHVSCFRCKACQAVLNG 247
            |..||.                   .::|||||..:|.||||:|||:|||:.||:||:|..||.|
  Rat   218 PKEATC-------------------SSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTG 263

  Fly   248 EYMGKDAVPYCEKCYQKGFGVKCAYCSRFISGKVLQAGDNHHFHPTCARCTKCGDPFGDGEEMYL 312
            ||:.||..|||||.||..|||||..|.:||:||||:|||. |:||:||||::|...|.:||||||
  Rat   264 EYISKDGSPYCEKDYQGLFGVKCEACHQFITGKVLEAGDK-HYHPSCARCSRCNQMFTEGEEMYL 327

  Fly   313 QGSAIWHPRC--------------------------------GPGP------------------- 326
            |||.:|||.|                                |..|
  Rat   328 QGSTVWHPDCKQSTKTEEKLRPPNIPRSSSDFFYPKSLIRRTGRSPALQHLSPPCLVNSNQNPRQ 392

  Fly   327 ----SESGIILNGGGGTSSVVGGASNGNF--TDTEC----------------------------- 356
                |...|....|   ||:.|...:..:  .|.|.
  Rat   393 PTRTSSESIYSRPG---SSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPF 454

  Fly   357 ------DRMSSSALSEM-YIRSRTPSFNGSLYSSSRKHYRTVSPGLILREYGRPNAEDISRIYTY 414
                  |:....:|.|. ...|.|||..|......|..:|:.|.|.|
  Rat   455 YTSGYEDKQDRQSLGESPRTLSPTPSAEGFQDGRDRMIHRSTSQGSI------------------ 501

  Fly   415 SYLTDAPHYLRKPIDPYDKTPLSP-HFHRP---------------SSYATTASNAGSVAGSRPPS 463
                ::|.|.|....|  .|..|| |||||               ||:::|.|:    ....||.
  Rat   502 ----NSPVYSRHSYTP--TTSRSPQHFHRPELLSPGVHRWSPLRTSSFSSTHSD----TRPNPPF 556

  Fly   464 R-----------PHSRTRSAMKVLVDAIRSETP----RPK-----SPGMN--------------- 493
            |           |.|...|.:....|: |..||    .||     ..|:|
  Rat   557 RHHFLPHVKGNEPSSGRNSPLPYRPDS-RPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHAALA 620

  Fly   494 -----NEEPIELSHYPAAKKPPPGEQPKIERDDFPAPPYPY---TDPERRRRYSDTYKGVPASDD 550
                 :|:.|:.|.:|||:.|.|.|.||||.|.:|.||...   |||.||          .:..:
  Rat   621 AQNKASEDIIKFSKFPAAQAPDPNEIPKIETDHWPGPPSLAAIGTDPRRR----------SSGRE 675

  Fly   551 EDENVENGKPNGKVKNGEEQQRLQREAEQLEKLNSGIGSAIAKDLKEHAKYRKWKQNNLDPRNAS 615
            |||.             |..:|.|.:.|||.|||||:|..|.|:..|       |:|.
  Rat   676 EDEE-------------ELLRRRQLQEEQLMKLNSGLGQLILKEEME-------KENR------- 713

  Fly   616 RTPSASKEPLYKLRYESPIGASPSRNLDHQKPFYEDEMFDRSTSYRGSLGKSLGNAPSYNAIHSY 680
                 .:..|...||:||:                               .|..:||      |.
  Rat   714 -----ERASLLASRYDSPL-------------------------------HSASHAP------SS 736

  Fly   681 RSPPKPGYGFKTTTLPYIRNGFSSDFS-YGGLGDKTHSTDLSCGKSEASVDSITEG--DRRALMG 742
            ::...||||......|     .|:||: |...||                  ::.|  |.:.|..
  Rat   737 KTSSLPGYGKSGLHRP-----VSTDFAQYNSYGD------------------VSGGVRDYQTLPD 778

  Fly   743 GDLPASSTYSGALSYHYPQAGLIRRSLPNM 772
            |.:||.....|.             |:|||
  Rat   779 GHMPAMRMDRGV-------------SMPNM 795

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Unc-115b	NP_731390.1	LIM1_abLIM	46..97	CDD:188713	26/50 (52%)
		LIM2_abLIM	102..157	CDD:188714	28/54 (52%)
		LIM3_abLIM	211..262	CDD:188715	33/50 (66%)
		LIM4_abLIM	270..326	CDD:188716	34/87 (39%)
Ablim1	NP_001382083.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	66	1.000	Domainoid score	I9669
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001360
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103132
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X852
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.810